Air & Asthma -- Pollution Changing Your DNA?

Researchers Find Polluted Air Affects DNA, Diminishes Immune Systems

October 1, 2011

Researchers found that polluted air has long-term effects on our DNA and diminishes the body's immune system. They also found that mothers exposed to air pollution, who had weaker immune systems combined with DNA damage, could actually pass the effects down to their children. Experts have not identified any medications to address these issues, but they plan to test whether the effects can be reversed by moving to a less polluted area.

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ASTHMA OR ALLERGIES? Asthma is a chronic disease affecting the airways that carry air in and out of the lungs. The interior walls of the airways become inflamed (swollen) and narrow so that less air can flow through the lung tissues. This in turn causes wheezing, coughing, tightness in the chest, and trouble breathing. Asthma is linked to allergies, although not everyone with asthma has allergies. People with allergies tend to react more strongly to the presence of allergens such as animal dander, dust mites, pollen or mold, as well as cigarette smoke and air pollution.

WHAT IS SMOG? Smog is a mixture of air pollutants that form smoke and fog in the air. It is generally formed when ground-level ozone, fine particles, and other chemicals react on hot days. Ozone in the upper atmosphere protects the Earth from the sun's harmful ultraviolet rays, but at ground level, ozone is a highly irritating gas. It forms when two primary pollutants -- nitrogen oxides and volatile organic compounds -- react in sunlight and stagnant air. Most nitrogen oxides come from burning fossil fuels, while VOCs are gases that contain carbon, usually emitted by gasoline fumes and solvents, such as those found in some paints. Airborne particles, sometimes called aerosols, are microscopic particles of pollutants that can remain suspended in the air for a considerable length of time. Primary particles include windblown dust and soil, sea spray, pollen, and plant spores.

The Biophysical Society contributed to the information contained in the TV portion of this report.

This report has also been produced thanks to a generous grant from the Camille and Henry Dreyfus Foundation, Inc.

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New Insight Into Asthma-Air Pollution /p>

To Go Inside This Science:

Kari Nadeau MD, PhD
Associate Professor of Pediatrics 
Associate professor of Otolaryngology
Stanford University School of Medicine

Ellen Weiss
Biophysical Society
Phone:240-290-5606