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Stroke Stopper

Interventional Neuroradiologists Treat Brain Strokes with New Kind of Stent

April 1, 2006

A new "wingspan" stent helps restore blood flow for patients with intracranial atherosclerotic disease, or ICAD. Surgeons insert the stent up the leg arteries, guide it to the brain, then let its wire mesh expand, propping open a clogged blood vessel. The new stent, designed for the fragile, curvy arteries in the brain, replaces stiffer stents used in heart and neck vessels.

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Science Insider

Science behind the news is funded by a generous grant from the NSF

BACKGROUND: A new medical device can open clogged arteries in the brain, helping prevent strokes. Called the Wingspan Stent System, it is specifically designed to treat blockages caused by intracranial athlerosclerotic disease, a condition that causes strokes. While it won't address risk factors such as high blood pressure or high cholesterol, the device will significantly decrease a patient's risk of stroke.

WHAT ARE STENTS? A stent is essentially a small piece of metal "scaffolding" that pushes arterial plaque to the side and provides a framework to keep the blood vessel open so that the blood can flow freely through it. Stents have been used for many years to clear blockages in the arteries of the heart and neck. But arteries in the brain are fragile, with many more curves, so it is much harder to get the stent to the blockage site. Steel stents can injure those vessels. The Wingspan stent is made of an alloy of nickel and titanium, which puts less pressure on the blood vessel when it expands.

HOW IT WORKS: Neuroradiologists insert a catheter into an artery in the upper leg. Using digital X-rays for image guidance, they then navigate the catheter through the blood vessels to the site of the blockage in the brain. They then slowly inflate an angioplasty balloon to push away the plaque and put the stent in place to hold the vessel open.

ABOUT STROKES: The brain is made up of living cells that require a constant supply of nutrient- and oxygen-rich blood. Blockage or rupture of the blood vessels supply parts of the brain cause most strokes. A stroke occurs when brain tissue is deprived of blood and brain cells die from the lack of oxygen. Depending on which area of the brain is affected, a stroke can cause vision problems, speech problems, disability, even death. Traditionally, treatment for stroke-causing diseases involves blood-thinning drugs to prevent clots, but for patients with severe blockage, this may not be sufficient. Some temporary blockages only last minutes or hours, leading to mini-strokes. Mini-strokes are a sign of a serious problem and can lead to a permanent stroke if left untreated.

ABOUT BLOOD FLOW: The heart pumps blood through the arteries, capillaries and veins to provide oxygen and nutrients to every cell of the body, and also carries away waste products from those cells. The liquid portion of the blood is called plasma. It distributes various nutrients and chemicals throughout the body, diffusing into the tissues and cells. In general, they diffuse from areas of high concentration to areas of low concentration. Waste flows in the opposite direction and are removed in the kidneys or the lungs. Blood pressure pushes fluid out of blood vessels. This is balanced by something called oncotic pressure, which keeps fluid inside the blood vessels so that the body maintains a constant volume of blood.

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Did you know?...

The human body contains about 5 liters (5.3 quarts) of blood and makes up about 7 to 8 percent of a person's body weight.

More information on this story

Dr. Abraham Obuchowski
University of Maryland Medical Center
Baltimore, MD
Tel: 410-328-UMMS (8667)


© 2008 American Institute of Physics