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Wireless Tumor Tracker

Engineers Devise Implantable Dosimeter to Track Success of Radiation Therapy

September 1, 2006

Radiologists could soon measure the amount of radiation exposure experienced by different tissues using an implantable capsule. The device contains a small dosimeter and sends radiation exposure data back wirelessly. The method is safer and cheaper than imaging the organs during therapy using X-rays. The current prototype is the size of a dime, but electrical and computer engineers hope to bring that down to the size of a grain of rice.

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Science behind the news is funded by a generous grant from the NSF

BACKGROUND: Engineers at Purdue University are creating a wireless device the size of a rice grain that could be implanted into tumors to tell doctors the precise dose of radiation received and locate the exact position of tumors during treatment. Doctors could use the wireless technology to precisely track a tumor by using electrical coils placed around the body to pinpoint the location of the electronic device inside the body. The prototype device has been tested with a radioactive material called cesium.

HOW IT WORKS: The device is called a "passive wireless transponder," and works much like a small tuning circuit in a radio. It has no batteries and can be activated with electrical coils placed next to the body, and will be sealed airtight so it can stay in the body indefinitely. Along with the wireless tracking technology, the device contains a miniature version of the dosimeters worn by people who work in jobs involving radioactivity to monitor their exposure. The technology operates on the same principle as the electric microphones commonly found in consumer electronics. The microphones contain a membrane that vibrates in response to sound waves. Between the membrane and a metal plate is an air gap that stores electricity. As the membrane vibrates, the size of the air gap increases and decreases. This changes its capacity to store energy, altering the flow of electric current through the circuit. This in turn creates a signal that transmits the information stored in the dosimeter to a receiver.

THE PROBLEM: There is currently no way to determine the exact dose of radiation that reaches a tumor. Also, most organs shift inside the body depending on whether a person is sitting or lying down, which causes the tumor to shift also. Imaging systems are used to get a 3D fix on a tumor's shifting position, but such methods are difficult to use during radiation therapy, are expensive, and may require X-rays, which can damage surrounding tissue over repeated uses.

WHAT ARE MEMS? Micro-Electro-Mechanical Systems (MEMS) are tiny functional machine systems in which various components -- microscale gears, pumps, sensors, pipes and actuators -- are integrated onto a single chip. Examples of MEMS include ink-jet printers, accelerometers in cars, pressure sensors, high-precision optics, and microfluidics. The most common application of the latter is in "lab on a chip" technology, devices which can process tiny chemical or DNA samples for medical diagnoses.

IEEE-USA contributed to the information contained in the TV portion of this report.

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More information on this story

Babak Ziaie
Engineer, Purdue University
Tel: 765-494-0725
bziaie@purdue.edu

IEEE-USA
Washington, DC 20036-5104
202-530-8353
ieeeusa@ieee.org


© 2008 American Institute of Physics