About DBIS   | Story archive   | Contact DBIS  | DBIS home

Tracking Alzheimer's

Neuroscientists Find Evidence of Alzheimer's in Living Patients with Radioactive Tracers

August 1, 2009

Neuroscientists are able to detect the indicators of Alzheimer's disease early on in living patients. Traditionally, the plaques and tangles that mark the disease are only identifiable post-mortem but neuroscientists developed a technology that allow them to see these abnormal plaque build ups in the brain. To do this, researchers inject a radioactive tracer into a patient's arm. The tracer reaches the brain and binds to the plaques A PET scan reveals these lesions in the brain's memory regions.

read the full story...

Science Insider

ABOUT ALZHEIMER'S: Alzheimer's is the most common form of dementia, a brain disorder that primarily affects the elderly. Scientists still aren't sure what causes the disease, and there is no cure. It is named after a German doctor, Alois Alzheimer, who noticed (in 1906) anomalies in the brain tissue of a woman who had died of a strange mental illness. There were abnormal clumps (called amyloid plaques) and tangled bundles of fibers, both of which are the most common signs of Alzheimer's. Other brain changes can occur. Nerve cells die in areas of the brain vital to memory and other mental abilities, and the connections between nerve cells are disrupted, impairing thinking and memory.

SYMPTOMS: Alzheimer's is a slow-moving disease, and in its earliest stages, may merely appear to be mild forgetfulness, and confused with age-related memory change. There may be problems remembering recent events or activities, or the names of familiar people or objects. As the disease progresses, the forgetfulness becomes more severe, interfering with daily activities, such as brushing one's teeth. There are problems speaking, understanding, reading or writing, and eventually the brain damage becomes so severe as to require total care.

The American Association of Physicists in Medicine contributed to the information contained in the TV portion of this report.

Video help

Latest stories

  • A Satellite Named Violet and a Student Named Amanda
  • Behind the Scenes with the K-Team
  • Deep Space Discoveries
  • Dogs Fighting Cancer
  • Earthquake! What's Your Risk

More information on this story

On the Web: UCLA Center on Aging

To Go Inside This Science:
Rachel Champeau
Public Affairs
University of California - Los Angeles
rchampeau@mednet.ucla.edu
310-794-2270

Dr. Sudarshan Chamakuri
Medical Physicist
American Association of Physicists in Medicine
RADIATIONTHERAPY@HOTMAIL.COM


© 2011 American Institute of Physics