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 Chip-Based Protein Studies



Schematic of a chip designed to study the flow of ions in and out of cells through single proteins. An electrolytic solution on both sides of the chip is electricallly contacted via electrodes. (A) The measured current response to a voltage pulse of 10 millivolts. (B) The same voltage pulse is applied after a cell is sealed onto the aperature by suction. (C) Closeup shows the mechanically and electrically tight contact of the cell membrane. (Courtesy of CeNS)

Reported by: Fertig et al., Applied Physics Letters, 16 December 2002.

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