Latest Jobs from Physics Today

Schenefeld (bei Hamburg), Germany, European XFEL is an international non-profit company located in the Hamburg area in Germany. It operates a 3.4 km-long X?ray laser, which produces X?rays of unique quality for studies in physics, chemistry, the life sciences, materials research and other disciplines. The diverse scientific facilities at European XFEL enable scientists from across the globe to carry out a wide range of experimental techniques. For our Detector group we are looking for an Detector Calibration and Characterisation Scientist (m/f/d) The Position Be responsible for the development and improvement of the detector calibration and characterization algorithms and tools, focusing on their standardization and optimization Act as the point of contact to the Data Analysis group, and instrument detector scientists, regarding the integration of calibration and characterization tools in the calibration services and infrastructure Work with detector and instrument scientists to define requirements, develop and validate the calibration and characterization tools to be integrated in the calibration services for the new detectors Review and improve user interfaces for the calibration services Prepare new deployments and testing of the new calibration devices Requirements MSc/PhD in Physics or MSc/PhD in Engineering for software development Strong programming experience within a scientific context Experience in large scale data processing Experience in GPU programming (CUDA) is considered an asset Experience with HDF5 is considered as an asset Good knowledge of C++ is considered as an asset Experience with git and GitLab is considered an asset Good communication skills and ability to work in a structured way in a multilingual, multidisciplinary team with English as working language For additional information, please contact Monica Turcato ( [email protected] ). Working place will be Schenefeld, in the Hamburg metropolitan area. General information on working in Germany, the Hamburg area and the European XFEL can be found  here . Our offer Become part of a vibrant international and multicultural team of scientists, engineers, technical and administrative staff. Be involved in cutting edge scientific and technical progress and participate in our international networks. Experience our atmosphere of tolerance and respect. Salary and benefits are similar to those of public service organizations in Germany, this includes for example: family-friendly working environment (e.g. additional childcare days) flexible working times and option for work from home depending on tasks 30 days of vacation, 24th and 31st of December are free as a courtesy of the employer extensive relocation benefits generous company pension scheme (6,45% of monthly salary) monthly social events and subsidized company restaurant partially financed job-tickets for public transportation extensive training opportunities incl. subsidized English and German language classes Easy and free access to a mental health platform to support your well?being Our company language is English. Reference number: S-571 Duration:  This appointment is initially limited to 5 years, a permanent extension will be possible by later decision. Application Please apply  online  and provide your CV and a motivation letter in English as well as any reference letters. The European XFEL GmbH is an equal opportunity and affirmative action employer and we promote and support diverse and heterogenous teams. Applicants with disabilities will be given preference over other equally qualified applicants. Apply now Deadline:  15 January 2025 European XFEL GmbH Holzkoppel 4, 22869 Schenefeld, Germany www.xfel.eu

Livermore, California, We have an opening for a senior scientist to lead antibody medical countermeasure development, joining ongoing innovative projects developing biologics against infectious diseases. You will be responsible for overseeing the development of antibody drug products from initial concept through to initial testing and handoff to partners for drug trails. You will lead activities conducted by cross-functional, interdisciplinary teams, including exploring technical feasibility, developing strategy, performing laboratory validation, and anticipating follow on regulatory requirements toward IND filing. Preferred candidates will have extensive experience with infectious disease research as well as experience managing translational research processes aimed at preparing biologics for pre-clinical trials. This position is in the Biosciences and Biotechnology Division. You will: Lead the development of antibody drug products. This includes coordinating and leading subject matter experts to assess technical feasibility and strategic benefits of potential new antibody products, working with team leads responsible for computational antibody design as well as leads responsible for antibody production and characterization. Collaborate with cross-functional, interdisciplinary, teams, including R&D efforts on new assay development and new laboratory technologies. Collaborate with external partners that provide reagents, assays, and/or protein production capabilities. Develop product development strategies, including working with project managers to define and track highly complex multi-year project plans, timelines, and budgets. Prepare scientific reports summarizing results from highly complex research activities performed onsite and with partner organizations. Work with antibody production team to oversee recombinant mammalian and bacterial protein expression and purification. Interface with computational teams performing computational design. Lead multi-location research teams Anticipate project shortcomings in advance and direct resources to develop effective solutions to improve efficiency in key areas relevant antibody design and discovery. Share research results in peer-reviewed journals Develop and maintain relationships with external partners and collaborators. Stay up-to-date with industry trends and advancements in antibody technology. Initiate and/or lead collaborative projects requiring involvement of a broader scientific community. Perform other duties as assigned. Ph.D. in Molecular Biology, Cell Biology, or related field the equivalent combination of education and related experience. Highly advanced experience in antibody product development for infectious disease countermeasures, including experience in antibody generation and development, assay design, and antibody purification Substantial knowledge of cell biology, molecular biology, and biotechnology Expert with laboratory management, including molecular biology and cell biology Substantial experience with recombinant mammalian and bacterial protein expression and purification Expert leadership, communication, and project management skills. Significant experience developing and managing workflows for high throughput antibody production and screening platforms. Expert written, verbal communication and interpersonal skills necessary to deliver presentations, prepare written reports and to interact with a diverse set of scientists, engineers, and other technical and administrative staff. Additional desired qualifications: Significant experience with regulatory submissions and compliance Proven track record of leading cross-functional teams and developing successful product development strategies Expertise in library display technologies for high throughput screening, e.g., mammalian cell-based expression/display, yeast display, and/or other platforms. Extensive experience with additional protein purification and characterization techniques.

Livermore, California, We have multiple openings for graduate students and for students who have received a bachelor's or master's degree to engage in practical research experience to further their educational goals. You will conduct research in the following scientific fields: organic/inorganic synthesis, analytical, computational, materials characterization, actinide materials, optical materials science; electrochemistry; materials chemistry and physics; computational chemistry and materials science; nanoscale materials synthesis and characterization and metallurgy. These positions are in Materials Science Division in the Materials and Chemistry Institute. You will Work with scientists on projects involving hands-on work in a laboratory, computation, or data analysis. Conduct research in assigned area, under limited direction and supervision. Perform technical assignments of a basic degree of complexity and providing advanced technical support to scientist in scientific research and development projects. Present work through presentations and/or poster sessions. Must be a continuing college or university student in good standing at an accredited institution pursuing a graduate degree or a recent graduate with a bachelor's or master's degree in chemistry, materials sciences, computational chemistry, or a related field. Demonstrated academic achievement in chemistry, materials sciences, computational chemistry, or related field. Experience applying basic scientific principles to solve technical problems. Demonstrated effective communication skills. Ability to present and communicate concepts and ideas. Experience working with personal computers and familiarity with Word, Excel and PowerPoint. Ability to work in a team environment. Qualifications We Desire Broad knowledge of chemistry and materials. GPA of 3.0 or above.

Livermore, California, We have multiple openings for undergraduate students to engage in practical research experience to further their educational goals. Opportunities include conducting research in the following scientific fields: organic/inorganic synthesis, analytical, computational, materials characterization, actinide materials, optical materials science; electrochemistry; materials chemistry and physics; computational chemistry and materials science; nanoscale materials synthesis and characterization and metallurgy. These positions are in the Materials Science Division and part of the Materials and Chemistry Institute. You will Work with scientists on projects involving hands-on work in a laboratory, computation, or data analysis. Participate in research under close supervision in assigned area. Gather and analyze the data or information in support of scientific research. Presenting work through presentations. Must be a continuing college or university student in good standing at an accredited institution pursuing an undergraduate degree in chemistry, materials sciences, computational chemistry, or related field. Ability to apply basic engineering, scientific, or physics principles to solve technical problems. Demonstrated effective communication skills. Ability to present and communicate concepts and ideas. Experience working with personal computers and familiarity with Word, Excel and PowerPoint. Ability to work in a team environment. Qualifications We Desire Knowledge of chemistry and materials. GPA of 3.0 or above.

Livermore, California, NOTE: This is a two-year Postdoctoral appointment with the possibility of extension to a maximum of three years. We are seeking a dedicated and hardworking postdoctoral researcher to conduct research in the field of synthetic biology for biocontainment of genetically modified microorganisms. You will actively participate in research to develop biocontainment circuits in environmentally relevant bacteria and build and screen libraries for protein redesign. This position is in the Microbial systems or Synthetic biology group in the Biosciences and Biotechnology Division. In this role you will Conduct fundamental research in microbial synthetic biology. Employ state of the art library geneneration and develop high throughput approaches to assay the functionality of protein variants and microbial fitness. Employ synthetic biology to implement biological circuits in environmental microorganisms and characterize efficacy in test beds of increasing complexity. Engineer microbial communities for robust function. Develop research plans, generate results, and publish peer-reviewed papers. Work with other scientists to write proposals and expand our program into new areas aligned with your expertise and interests. Write reports to funding agencies and participate in scientific conferences. Pursue independent (but complementary) research interests and interact with a broad spectrum of scientists internally and externally to the Laboratory. Publish research results in peer-reviewed scientific or technical journals and present results at external conferences, seminars, and/or technical meeting. Perform other duties as assigned. PhD in Biological Sciences, Bioengineering, or a relevant field with a strong emphasis in synthetic biology and microbiology. Expertise and knowledge in bacterial genetics and physiology Experience in engineering bacterial strains for environmental function. This might include design, assembly, and modeling of genetic circuits. Experience with high throughput screening/selection methods Ability to develop independent research projects as demonstrated through publication of peer-reviewed literature. Proficient verbal and written communication and interpersonal skills to collaborate effectively in a multidisciplinary team environment and present and explain technical information. Qualifications we desire Experience with microbial evolution approaches (e.g., adaptive laboratory evolution) Experience with next-generation sequencing (NGS) execution and/or analysis Experience with in silico protein design/engineering and/or directed experimental evolution of proteins Experience with gene editing in non-model strains (non- E. coli systems). Experience with bacterial signaling systems (e.g., two component systems, quorum sensing systems) Experience with synthetic microbial communities for bioproduction or environmental application Experience in bioinformatics and/or proficiency in programming in one or more of the following languages: Python, Julia, C, C++, R, Java, or Matlab

Livermore, California, We have an opening for an Associate Program Leader (APL) for Cyber Systems and Infrastructure Assessments to lead a dynamic, multidisciplinary team of intelligence analysts and technical experts conducting all source analysis in support of national security interests. As part of the Science and Technology Assessments (STA) Program's management team, you will have execution responsibility for a diverse portfolio of scientific and technical intelligence activities that supports multiple stakeholders across the Intelligence Community and national security enterprise. This position is in the Global Security (GS) Principal Directorate's Z Program and programmatically reports to the STA Program Leader. This position will be filled at either the SEL.4 or SEL.5 level depending on your qualifications. Additional job responsibilities (outlined below) will be assigned if you are selected at the higher level. In this role you will Lead the program's research agenda, including producing highly technical, finished intelligence analysis, reports, and briefings. Develop and implement an integrated strategy for research and production, consistent with overall programmatic objectives. Lead, manage, and coordinate Principal Investigators (PIs) and all-source intelligence analytic projects across the cyber systems and infrastructure assessments mission space, ensuring that projects are conducted to the highest standards of technical and analytical quality and fiscal management, and meet all Laboratory safety and security requirements. Develop and track project execution plans for the program's assigned analytic projects, including allocation and monitoring of available resources, personnel, and budgets. Conduct independent research on sensitive, politically significant national security topics, with a focus on cyber, critical infrastructure, and advanced energy technologies. Write reports and present analytic findings that adhere to intelligence community analytic standards in support of sponsor and stakeholder objectives. Serve as the point of contact for relevant technical and policy areas associated with the program's mission areas and sponsors as defined by the STA Program Leader. Represent the program with sponsors and other U.S. Government (USG) organizations, traveling, as necessary. Build, maintain, and enhance relationships with sponsors, customers, and stakeholders to ensure exquisite execution of projects and satisfaction of commitments while developing new program opportunities. Recruit staff in collaboration with counterparts, management, and matrix organizations to support the mission area and assist the STA Program Leader and Mission Managers to balance resources with other laboratory mission areas. Maintain and ensure appropriate quality standards of complex projects, program deliverables, and research and development activities including reviewing, coordinating, and approving publications and presentations. Perform other duties as assigned. Additional job responsibilities, at the SEL.5 level Develop innovative concepts and provide expert leadership, technical vision, and strategic planning for both analytic and scientific research and development activities. Ensure project execution meets and exceeds customer expectations, as well as identify new opportunities, goals, and application areas by leading the development of proposals and engaging with senior stakeholders and program management personnel. Develop and implement new innovative analytical capabilities within the program and apply them against an expanding portfolio. Influence strategic decisions made by senior management and external customers at the national level. This position requires an active DOE Q-level clearance or active Top-Secret clearance issued by another U.S. government agency at the time of hire and must have the ability to obtain and maintain SCI access. Master's Degree in a relevant scientific or engineering discipline, political science, international relations, or the equivalent combination of education and significant related experience and demonstrated ability to lead the application and development of analytic principles, theories, and concepts in a creative and innovative fashion. Subject matter expert knowledge and significant experience working within or with the Intelligence Community (IC) and with scientific and technological issues associated with national security, to include energy, cyber, critical infrastructure, and other advanced technology issues. Substantial experience managing, leading, and supervising multidisciplinary projects and teams and delivering analytic support to external programmatic sponsors. Expert knowledge of Intelligence Community (IC) requirements, standards, and practices, including Sensitive Compartmented Information (SCI) security marking, intelligence oversight and compliance, and related security practices. Substantial experience working in a classified environment with highly complex, multi-agency security requirements and with both classified and unclassified subject matter. Substantial experience with programs and projects for national security mission applications and understanding of national security mission requirements and related issues. Significant knowledge of all source intelligence analysis and tradecraft with a demonstrated track record of authoring and contributing to intelligence community and/or national security publications. Expert verbal and written communication skills necessary to effectively present, explain, and advise senior management and external sponsors and customers, including preparing and presenting proposals and analytic reports. Ability and willingness to travel in support of the program. Additional qualifications, at the SEL.5 level Ph.D. in a relevant scientific or engineering discipline, political science, international relations, or the equivalent combination of education and significant related experience. Expert knowledge of and extensive experience leading and developing positions on, and performing assessments and analyses related to the national security aspects of energy, cyber, critical infrastructure, and other advanced technology issues. Technical knowledge of advancements and emerging technologies related to energy, cyber, and infrastructure systems that have global impact and the ability to champion, lead, and develop innovative principles, theories, and concepts.

Livermore, California, We are seeking exceptional Physical Scientists and Engineers with backgrounds in fields such as plasma physics, radiation transport, atomic physics, nuclear physics, physical chemistry, condensed matter physics, computational physics, or hydrodynamics. Our national-security mission encompasses aspects of computational, theoretical, and experimental physics associated with the complex processes of nuclear explosives. Under limited direction, you will be responsible for advancing our understanding and developing methodologies for important national-security challenges. These positions are in the Design Physics Division within the Strategic Deterrence Directorate. These positions may offer a hybrid schedule, which includes the flexibility to work from home one or more days per week, after a probationary period. The specifics of the hybrid schedule, including the exact number of days required in the office and virtual work options may vary based on the needs of the team and the organization. These positions will be filled at either level based on knowledge and related experience as assessed by the hiring team. Additional job responsibilities (outlined below) will be assigned if hired at the higher level. In this role, you will Assess the complex physics interactions that take place in nuclear explosion. Design and provide analysis of experiments exploring the physics of nuclear explosives. Simulate weapons phenomena and perform weapons assessment and certification tasks using physical models in computer codes. Define and implement stockpile stewardship for specific weapons systems. Present and disseminate research results at scientific conferences and in peer-reviewed publications, in both open and classified environments, internal and external to LLNL. Responsibilities may also include interacting with external stakeholders, both at DOE/NNSA and across the broader interagency, as well as via offsite assignments. Develop expertise in interrelated fields of physics important to weapons assessment and certification. Travel minimally or substantially based on needs of projects. Recognize and support plans to promote and foster a culture of inclusion, diversity, equity, and accountability within the workplace. Perform other duties as assigned. Additional job responsibilities at the SES.3 Level Independently develop, assess and provide in depth analysis of the complex physics interactions that take place in nuclear explosion where problems may not be well defined. Work as technical expert on multidisciplinary team. Guide the analysis and lead the design of experiments exploring the physics of nuclear explosives. Ability to obtain and maintain a U.S. DOE Q-level security clearance which requires U.S. Citizenship. PhD in physics, engineering, or a related field or equivalent level of demonstrated knowledge. Demonstrated record of completing outstanding research in relevant areas of physics and engineering. Experience with computer-based design and analysis of experiments. Demonstrated aptitude for mastering new fields of physics; a record of creativity, physical insight, and breadth of understanding in applications of complex physical processes. Experience in using advanced computational facilities for applied physics analysis and conducting applied physics research. Proficient verbal and written communication and presentation skills necessary to author technical and scientific reports, publications, invited papers, and to deliver scientific presentations. Experience working effectively independently and in a multidisciplinary, team-research environment. Demonstrated self-motivation and initiative in addressing challenging problems. Additional qualifications at the SES.3 Level Advanced knowledge of physics, engineering, or a related field. Significant experience and ability to lead independent work conducting applied physics research. Demonstrated record of leading top quality research in relevant areas of physics and engineering. Qualifications we desire Demonstrated ability/commitment to promote and value inclusion, diversity, equity, and accountability principles in the workplace. Please include a personalized cover letter with your application, highlighting your qualifications and why you're interested in this position.

Livermore, California, We have openings for Computational Physicists to pursue challenges relevant to national security in the development of multi-physics simulation codes. Under consultative direction you will collaborate as part of an interdisciplinary code development team in advancing the state of the art in large-scale multi-physics simulation. The national security mission involves developing simulation capabilities for Stockpile Stewardship, nuclear counter-terrorism, conventional weapons, and high energy density physics experiments. The code development focus is on models and algorithms for use in high-performance computing on the latest large-scale parallel computing platforms. You will act as a scientific/technical leader as part of large projects/programs, contribute to the development of innovative principles and ideas, will play a role in attracting and retaining projects, programs, and funding due to degree of technical expertise. These positions are in the Design Physics Division within the Strategic Deterrence Directorate. These positions may offer a hybrid schedule, which includes the flexibility to work from home one or more days per week, after a probationary period. The specifics of the hybrid schedule, including the exact number of days required in the office and virtual work options may vary based on the needs of the team and the organization. In this role, you will Develop algorithms and simulation tools to advance the state of the art in multi-physics simulation for a large variety of physical processes in 2D and 3D, where problems are not well defined. Independently develop and/or provide in-depth analysis of physics capabilities in support of a diverse user community using advanced simulation tools to solve highly complex problems that may not be well defined. Provide advanced technical support, informal training, and guidance to code users in the application of simulation tools developed. Collaborate in the development of simulation tools and direct/influence the strategy and technical direction of research activities as part of a multi-disciplinary team. Present and disseminate advanced research results at scientific conferences and in peer-reviewed publications, in both open and classified environments, internal and external to LLNL. Promote and support plans to promote diversity, equity, and inclusion within the program. Set broad technical strategies and/or direct multi-disciplinary teams to achieve program goals. Perform other duties as assigned. Ability to secure and maintain a U.S. DOE Q-level clearance which requires U.S. citizenship. PhD in one or more of these specialized fields: physics, mathematics, engineering, or related field or the equivalent combination of education and related experience. Subject matter expert knowledge of highly advanced concepts to include experience and ability to lead independent work in one or more science disciplines, such as shock hydrodynamics, fluid mechanics, material behavior, particle transport, radiation transport, plasma physics. Significant experience evaluating algorithms and methods for their fitness for a particular task, as well as developing and implementing new numerical algorithms. Significant experience developing and supporting and/or leading multi-dimensional numerical simulation and demonstrated analytical and conceptual skills and creativity. Advanced programming experience/fluency in Python, FORTRAN, C and/or C++ and significant experience developing and implementing algorithms for massively-parallel computer architectures. Effective verbal and written communication skills and experience authoring high-quality reports/publications and delivering effective technical presentations. Significant experience working independently and in a team-research environment effectively. Significant experience at the expert level in the development of principles, theories, concepts, and techniques relevant to applied physics research and experience converting theory into models or algorithms appropriate for numerical simulation. Qualifications we desire Demonstrated experience implementing plans that promote and value inclusion, diversity, equity, and accountability principles in the workplace.

Livermore, California, We have multiple openings for Design Physicists who are exceptional physical scientists and engineers with backgrounds in fields such as plasma physics, radiation transport, atomic physics, nuclear physics, physical chemistry, condensed matter physics, computational physics, or hydrodynamics. Our national-security mission encompasses aspects of computational, theoretical, and experimental physics associated with the complex processes of nuclear explosives. Under limited direction, you will be responsible for advancing our understanding and developing methodologies for important national-security challenges. These positions are in the Design Physics Division within the Strategic Deterrence Directorate. These positions may offer a hybrid schedule, which includes the flexibility to work from home one or more days per week, after a probationary period. The specifics of the hybrid schedule, including the exact number of days required in the office and virtual work options may vary based on the needs of the team and the organization. These positions will be filled at either level based on knowledge and related experience as assessed by the hiring team. Additional job responsibilities (outlined below) will be assigned if hired at the higher level. In this role, you will Design and provide analysis of complex experiments exploring the physics of nuclear explosives. Simulate weapons phenomena and perform weapons assessment and certification tasks using physical models in computer codes. Participate in the assessment of foreign nuclear weapon systems. Present and disseminate research results at scientific conferences and in peer-reviewed publications, in both open and classified environments, internal and external to LLNL. Positively represent the Program and Laboratory demonstrating advanced verbal and written skills. Responsibilities may also include interacting with external stakeholders, both at NNSA and across the broader interagency, via offsite assignments. Develop expertise in interrelated fields of physics important to weapons assessment and certification. Lead independent work conducting applied physics research. Lead and mentor staff as part of a multidisciplinary team. Lead top quality research in relevant areas of physics and engineering. Problem-solve and make decisions necessary to independently address challenging problems. Recognize and support plans to promote and foster a culture of inclusion, diversity, equity, and accountability within the workplace. Perform other duties as assigned. Additional job responsibilities at the SES.4 Level Assess the highly complex physics interactions that take place in a nuclear explosion. Design and provide in depth analysis of experiments exploring the physics of nuclear explosives. Define and implement stockpile stewardship for specific weapons systems. Simulate weapons phenomena and perform highly advanced weapons assessment and certification tasks using physical models in computer codes. Ability to maintain a U.S. DOE Q-level security which requires U.S. citizenship. Master's degree in physics, engineering, or related field or equivalent combination of education and related experience. Significant experience conducting applied physics research. Demonstrated record of completing outstanding research in relevant areas of physics and engineering. Significant experience with advanced computer-based design and analysis of experiments. Demonstrated aptitude for mastering new fields of physics; a record of creativity, physical insight, and breadth of understanding in advanced applications of complex physical processes. Significant experience in using advanced computational facilities for applied physics analysis. Advanced verbal and written communication and presentation skills necessary to author advanced technical and scientific reports, publications, invited papers, and to deliver scientific presentations. Significant experience working effectively independently and in a multidisciplinary, team-research environment. Demonstrated self-motivation and initiative in addressing challenging problems. Additional qualifications at the SES.4 Level Substantial experience presenting and disseminate highly advanced research results at scientific conferences and peer-reviewed publications, in open and classified environments, internal and external to LLNL. Substantial experience communicating results of work with external sponsors. Substantial experience developing innovative methods to expand knowledge of interrelated fields of highly advanced physics important to weapons assessment and certification. Substantial experience setting specific strategies and/or directing multi-disciplinary teams to achieve program goals. Qualifications we desire Demonstrated subject matter expert knowledgeable of highly advanced concepts to include experience and ability to lead independent work conducting applied physics research in one or more of the following fields: plasma physics, radiation transport, atomic physics, nuclear physics, and hydrodynamics. Significant experience with highly advanced computer-based design and analysis of highly complex experiments. Extensive experience at the expert level in the development of principles, theories, concepts, and techniques relevant to applied physics research. Demonstrated ability/commitment to promote and value inclusion, diversity, equity and accountability principles in the workplace. Please include a personalized cover letter with your application, highlighting your qualifications and why you're interested in this position.

Livermore, California, We have multiple openings for Inertial Confinement Fusion Physicists to become part of the team working on the grand challenge of achieving thermonuclear ignition on the National Ignition Facility (NIF). This research requires working closely with individuals from other disciplines, such as laser experimentalists, laser scientists, target fabrication specialists and NIF Project scientists and engineers, as well as other target designers and theorists. These positions are in the Design Physics Division within the Strategic Deterrence (SD) Directorate. This position may offer a hybrid schedule, which includes the flexibility to work from home one or more days per week, after a probationary period. The specifics of the hybrid schedule, including the exact number of days required in the office and virtual work options, may vary based on the needs of the team and the organization. These positions will be filled at either level based on knowledge and related experience as assessed by the hiring team. Additional job responsibilities (outlined below) will be assigned if hired at the higher level. In this role, you will Plan, analyze and interpret NIF laser experiments in support of the effort to achieve ignition on NIF principally with large computer codes, but also with analytic modeling. Perform computational and theoretical analyses that extrapolate our current understanding of ignition related physics to NIF and beyond. Successfully work as part of an interdisciplinary team on ICF project activities. Present research results in scientific meetings, peer reviews, and publications. Responsibilities may also include interacting with external stakeholders, both at NNSA and across the broader interagency, via offsite assignments. Promote and support plans to promote diversity, equity, and inclusion within the program. Perform other duties as assigned. Additional responsibilities at the SES.3 Level Independently develop and/or provide in depth analysis of NIF laser experiments in support of the effort to achieve ignition on NIF principally with large computer codes, but also with analytic modeling where complex problems may not be well defined. Work as technical expert on a multidisciplinary team. Ability to maintain a U.S. DOE Q-level security which requires U.S. citizenship. PhD in physics or related field, or the equivalent combination of education and related experience. Comprehensive knowledge of plasma physics, hydrodynamics, or astrophysics. Experience in computational modeling of complex systems. Experience developing creative solutions to complex problems. Demonstrated ability to deliver a high quality, polished product in a timely manner. Proficient written and verbal communication skills demonstrated by a record of publications, invited papers, or teaching experience. Demonstrated ability to interact effectively in an interdisciplinary team of scientists as well as independently. Additional qualifications at the SES.3 Level Advanced knowledge of physics, plasma physics, hydrodynamics, or astrophysics or a related field. Experience leading and mentoring as part of a multidisciplinary team. Demonstrated record of completing and/or leading top-quality research in relevant areas of physics and engineering. Qualifications We Desire Experience with the use of large two and three-dimensional computer codes. Demonstrated ability/commitment to valuing diversity, equity, and inclusion principles in the workplace. Please include a personalized cover letter with your application, highlighting your qualifications and why you're interested in this position.

Livermore, California, We have multiple openings for Computational Physicists aiming to improve national security through the development of simulation codes for world class supercomputing architectures. You will collaborate as part of an interdisciplinary team in advancing state-of-the-art physics simulation capabilities. Applications may include inertial confinement fusion, high-energy density physics, nuclear/conventional weapons, or nuclear counterterrorism. Our projects span the range from smaller, focused research codes/modules to multi-physics, multi-application production codes. These positions are in the Design Physics Division within the Strategic Deterrence Directorate. These positions may offer a hybrid schedule, which includes the flexibility to work from home one or more days per week, after a probationary period. The specifics of the hybrid schedule, including the exact number of days required in the office and virtual work options may vary based on the needs of the team and the organization. These positions will be filled at either level based on knowledge and related experience as assessed by the hiring team. Additional job responsibilities (outlined below) will be assigned if hired at the higher level. In this role, you will Build simulation tools using modern software practices as part of a team. Develop models and algorithms to support physics capabilities for a diverse application space. Support users of your simulation tools. Share results through conferences, reports/publications, and potential interactions with collaborators. Recognize and support plans to promote and foster a culture of inclusion, diversity, equity, and accountability within the workplace. Perform other tasks as assigned. Additional responsibilities at the mid-career (SES.3) level Develop and critically assess physics capabilities to support applications requiring advanced simulation tools to solve complex problems. Collaborate as a technical expert on multidisciplinary teams. Set specific technical strategies to achieve project goals. Ability to secure and maintain a U.S. DOE Q-level security clearance which requires U.S. citizenship. PhD or equivalent level of proficiency in physics, mathematics, engineering, or related field. Proficiency in developing scientific applications in Python, C/C++, or FORTRAN. Proficiency in converting theory into computational models, implementing computational models, or evaluating computational algorithms and methods for their applicability. Effective verbal and written communication skills and experience authoring high-quality reports/publications and delivering effective technical presentations. Additional qualifications at the mid-career (SES.3) level Advanced knowledge of physics, mathematics, engineering, or a related field. Significant professional programming experience. Experience in leading, mentoring, and/or collaborating within teams. Advanced verbal and written communication skills and a demonstrated record of delivering top-quality research in relevant areas of science and engineering. Qualifications We Desire Expertise in one or more science disciplines, such as shock hydrodynamics, solid/fluid mechanics, materials science, particle transport, radiation transport, nuclear physics, plasma physics, or physical chemistry. Proficiency in developing and supporting multi-dimensional numerical simulation. Proficiency in developing scientific simulations for high-performance and/or heterogeneous computing systems (e.g., use of MPI, OpenMP, Cuda/HIP, or other HPC technologies). Proficiency in developing advanced technical solutions (e.g., numerical algorithms). Proficiency in working in a multidisciplinary team-research environment, demonstrating creativity and initiative in addressing challenging problems. Demonstrated ability/commitment to promote and value inclusion, diversity, equity, and accountability principles in the workplace. Please include a personalized cover letter with your application, highlighting your qualifications and why you're interested in this position.

Livermore, California, NOTE: This is a two-year Postdoctoral appointment with the possibility of extension to a maximum of three years. We are seeking a highly motivated P ostdoctoral Researcher to join our team in the field of structural vaccinology and computational immunology. The successful candidate will work at the nexus of physics-based modeling and machine learning techniques and apply state-of-the-art experimental evaluations. You will work in an interdisciplinary team that includes computational structural biologists, infectious disease biologists, immunologists, engineers, and others to create a novel capability for designing broadly protective vaccine antigens. We offer a stimulating and inclusive work environment that fosters innovation and encourages professional growth. Join us in our mission to advance vaccine development and make a positive impact on global health. In this role, you will: Conduct advanced independent research to design and construct vaccine candidates using both experimental and computational approaches Employ a variety of structural biology techniques, including X-ray crystallography and cryo-electron microscopy, to determine the 3D structures of vaccine candidates and their interactions with the immune system Use physics-based modeling, simulation, and machine learning techniques to predict protein-protein interactions, protein stability, and other biophysical properties Use high-throughput and automated protein expression systems and characterization assays to design and test vaccine immunogens in vitro Develop collaboration with a multi-disciplinary team of computational scientists, structural biologists, engineers, and immunologists to integrate computational models with experimental data internally and with external partners in academia, industry, and other national laboratories Publish research results in peer-reviewed scientific or technical journals and present results at external conferences, seminars, and/or technical meeting. Work with other scientists to write proposals and expand our program into new areas aligned with your expertise and interests PhD in Structural biology, biochemistry, biophysics, computer science, computational biology, computational physics, computational chemistry or equivalent combination of education and related experience. Experience with protein expression, purification, and structural biology techniques Advanced knowledge and significant experience in vaccine design and immunology Ability to work independently on defined research projects, as well as a member of a large team. Ability to develop independent research projects as demonstrated through publication of peer-reviewed manuscripts Ability to travel, as necessary, to interact with sponsors, customers and collaborators Advanced written, verbal communication and interpersonal skills necessary to deliver presentations, prepare written reports and to interact with a diverse set of scientists, engineers, and other technical and administrative staff. Qualifications We Desire: Experience in collaborating with experimental and computational biologists as well as understanding and using experimental data in combination with computational research Experience with computational modeling and simulation of protein structure and with other computational tools for describing or predicting biophysical properties of proteins Experience in developing and training machine-learning based models in high-performance computing systems. Experience computing binding affinity, stability and/or other metrics using scoring functions like Rosetta Demonstrated ability to manage and prioritize multiple tasks and deliver high-quality results within deadlines

Livermore, California, The Bioscience and Biotechnology Division within the Physical and Life Sciences Directorate LLNL is seeking to fill a position for a dedicated and hardworking Research Scientist with a background in cell biology with demonstrated experience in advanced cellular and tissue models (cardiac and neuronal), toxicology, electrophysiology and other advanced molecular biology approaches. In this position, you will direct and conduct advanced cell and animal biology research, contributing to our understanding cellular effects of physiological insults for mission relevant programs. Your role will involve working on defined research projects, where you will be expected to demonstrate initiative, resourcefulness, and a keen attention to detail within a multidisciplinary team of scientists. This position is in the Human Health Sciences Group in the Biosciences and Biotechnology Division. You will: Lead and implement in vitro experiments that include both 2D and 3D rat and human cell models Collaborate with other scientists for in vivo experiments Utilize advanced cell and molecular biology techniques to investigate and understand mechanisms of cellular injury and repair Evaluate large data sets to refine, inform, and design subsequent experiments. Conduct literature reviews on state-of-the-art approaches relevant to the problem being addressed. Train and mentor early career and technician level staff Collaborate and interact with inter-organizational contacts and/or external customers. Prepare and present technical reports Perform other duties as assigned. Ability to secure and maintain a U.S. DOE Q-level security clearance which requires U.S. Citizenship. Ph.D. in Cell Biology or related field, or the equivalent combination of education and related experience. Significant experience with human and rat cell cultures, with an emphasis on cardiac and neuronal cells or tissue models. Significant experience with electrophysiology, immunostaining, flow cytometry, and multi-omics (emphasis on single-cell RNA sequencing). Significant experience in elucidating mechanisms of cellular or tissue disfunction Proficiency in R for data analyses. Advanced understanding of statistics for longitudinal datasets. Practical experience with multi-omics sample preparation and analyses. Experience in a fast-paced environment and able to work both independently and as a team with a diverse set of scientists, engineers, and other technical and administrative staff. Proficient with common software (e.g., Microsoft Office applications) and able to quickly learn new software. Additional Desired Qualifications: Experience with animal models for toxicological assessment Experience with histology and immunohistochemistry

Livermore, California, NOTE: This is a two-year Postdoctoral appointment with the possibility of extension to a maximum of three years. We are seeking a postdoctoral researcher to conduct important research in the fields of synthetic biology and protein design. You will work collaboratively to experimentally evaluate cutting-edge tools to totally redesign bacterial proteins and explore sequence-function landscapes unseen by evolution. You will help develop and use an integrated computational and high-throughput experimental pipeline with high diversity protein variant libraries. The ideal candidate will have both experimental and computational expertise. This position will be advised by Dr. Sean Leonard in the Synthetic Biology group in the Biosciences and Biotechnology Division. You will Work as part of a team to conduct fundamental research in microbial synthetic biology and protein design. Use a variety of protein design tools to generate new, sequence-diverse proteins with desired functions. Use state of the art gene synthesis approaches to produce gene libraries. Develop, troubleshoot, and validate high throughput approaches to assay the function of computationally-designed protein variants. Read and evaluate relevant scientific literature. Work with other scientists to write proposals and expand our program into new areas aligned with your expertise and interests. Write reports to funding agencies and participate in scientific conferences. Pursue independent (but complementary) research interests and interact with a broad spectrum of scientists internally and externally to the Laboratory. Publish research results in peer-reviewed scientific or technical journals and present results at external conferences, seminars, and/or technical meetings. Perform other duties as assigned. PhD in Biological Sciences, Bioengineering, or a relevant field with an emphasis in synthetic biology, microbiology, or protein biochemistry. Documented publication record with at least 1 first-author publication in a peer-reviewed journal. Experience with high throughput experimental screening and selection methods in bacteria. Experience in library-scale cloning and engineering bacterial strain and other common molecular biology and microbiology laboratory techniques Ability to develop and complete independent research. Proficient verbal and written communication and interpersonal skills to collaborate effectively in a multidisciplinary team environment and to effectively present and explain technical information. Qualifications we desire Experience with computational protein design or enzyme engineering (e.g., rationale design and/or directed evolution). Experience in bioinformatics and/or proficiency in programming in one or more of the following: Python, R, UNIX command-line tools, or similar. Experience with the preparation and analysis of short- (Illumina) or long- (Nanopore) read sequencing libraries. Experience with laboratory automation (design or use of molecular biology protocols with liquid handling robots). Experience with biochemical investigation and characterization of protein function and activity.

Livermore, California, We have multiple openings for undergraduate students to engage in practical research experience to further their educational goals. Opportunities include conducting research in the following scientific fields: organic/inorganic synthesis, analytical, computational, materials characterization, actinide materials, optical materials science; electrochemistry; materials chemistry and physics; computational chemistry and materials science; nanoscale materials synthesis and characterization and metallurgy. These positions are in the Materials Science Division and part of the Materials and Chemistry Institute. You will Work with scientists on projects involving hands-on work in a laboratory, computation, or data analysis. Participate in research under close supervision in assigned area. Gather and analyze the data or information in support of scientific research. Presenting work through presentations. Must be a continuing college or university student in good standing at an accredited institution pursuing an undergraduate degree in chemistry, materials sciences, computational chemistry, or related field. Ability to apply basic engineering, scientific, or physics principles to solve technical problems. Demonstrated effective communication skills. Ability to present and communicate concepts and ideas. Experience working with personal computers and familiarity with Word, Excel and PowerPoint. Ability to work in a team environment. Qualifications We Desire Knowledge of chemistry and materials. GPA of 3.0 or above.

Livermore, California, We have multiple openings for graduate students to engage in practical research experience to further their educational goals in the Computational Chemistry and Materials Science Summer Institute. You will research projects in the development and application of methods in computational materials science, computational chemistry, and other related areas of computational science. These positions are in Materials Science Division and are virtual. You will Work alongside Lab scientists performing computational simulation data analysis. Under limited direction and supervision will conduct research in assigned area. Perform technical assignments of a basic degree of complexity and providing advanced technical support to scientist in scientific research and development projects. Virtually present work through presentations and/or poster sessions. Must be a continuing college or university student in good standing at an accredited institution pursuing a graduate degree in chemistry, materials sciences, computational chemistry, or related field. Demonstrated academic achievement in material science, computer science or a related field. Experience applying basic scientific principles to solve technical problems and knowledge of PC and/or Macintosh computers to translate and report scientific data. Demonstrated effective communication skills. Ability to present and communicate concepts and ideas. Experience working with personal computers and familiarity with Word, Excel and PowerPoint. Ability to work in a team environment. Qualifications We Desire Broad knowledge of material and/or computer science. GPA of 3.0 or above.

Livermore, California, We have an opening for a Technologist/Senior Technologist to provide design, assembly, installation, and operational support of complex laboratory equipment and systems within the Physical and Life Sciences Directorate. The majority of work will be in facilities and with equipment that present material hazards. This position is in the Nanoscale Integration Science Group within the Materials Science Division. This position requires full-time on-site presence due to the nature of the work. This position will be filled at either the 504.2 or 504.3 level depending on your qualifications. Additional job responsibilities (outlined below) will be assigned if you are selected at the higher level. You will Provide general support for the design, development, installation, and operational support for Materials Science Division research capabilities, including glove boxes, HEPA filters, and materials characterization equipment. Collaborate with technical staff and subject matter experts to install and upgrade experimental setups and perform maintenance, operations, repairs, and upgrades of existing equipment and systems. Work on equipment and in laboratories that routinely present chemical hazards including beryllium, radioactive material, lead, asbestos, and nanomaterials, as well as explosive hazards, biomaterial hazards, and electrical hazards. Assist in identifying solutions to moderately complex technical problems for a diverse range of laboratory equipment. Perform decontamination and decommissioning of legacy equipment. Work as an integral part of a results-oriented team on an ongoing basis. Work under general direction on well-defined small projects. Document work in lab notebooks and informal reports. Perform other duties as assigned. Additional job responsibilities, at the 504.3 level Work independently or with minimal direction on small projects and contribute to larger projects under general guidance. Write and maintain safety documentation for technical work. Routinely co-ordinate work activities with technical staff throughout the Materials Science Division and Physical and Life Sciences Directorate. Ability to secure and maintain DOE Q-level and SCI security clearances, which require U.S. Citizenship. AA/AS degree in Materials Science, Chemistry, Physics, Electrical or Mechanical Engineering, or related field or the equivalent combination of education and related experience. Experience working with hazardous materials. Elementary understanding of electrical, high vacuum, and pressure systems. Machining experience, including common machine and hand tools. Computer skills, including abilities in a variety of standard software programs. (e.g., Microsoft Office Suite, Microsoft Teams). Basic understanding of technologies, processes, and laboratory equipment and systems for Materials Science Division research capabilities. Effective communication skills, both verbal and written. Ability to work in a diverse team environment with scientific and technical personnel. Additional qualifications at the 504.3 level Experience using respiratory protection and familiarity with radioactive waste (LLW, TRU). Experience in writing or maintaining Work Planning and Control (e.g., standard operating procedures) documents. Basic understanding and experience with computer aided designed (CAD) software (e.g., Solidworks, AutoCAD). Qualifications We Desire Experience in the maintenance and installation of a diverse range of laboratory equipment and systems. Experience in the decontamination and decommissioning of laboratory equipment.

Livermore, California, NOTE: This is a flexible term position dependent on project funding. Current funding is expected for at least 2 years. The Bioscience and Biotechnology Division within the Physical and Life Sciences Directorate at LLNL is seeking to fill a position for a dedicated and hardworking Biosciences Technician with experience in neurobiology, cellular biology and/or molecular biology. In this position, you will provide technical support for establishing and evaluating 2D and 3D primary cultures of the nervous system and related animal research. In addition, you will support the preparation and processing of samples for multiomic analyses. Your role will involve working on defined research projects, where you will be expected to demonstrate initiative, resourcefulness, and a keen attention to detail within a team of scientists. This position is in the Human Health Sciences Group in the Biosciences and Biotechnology Division. You will: Follow protocols for isolating and establishing primary human and rodent neuronal and glia cultures. Maintain cell cultures and perform routine cell-based assays (e.g., electrophysiology, optical microscopy, immunostaining, preparation of samples other offline assays). Prepare and process samples for multiomic analysis, and perform transcriptional sequencing experiments (e.g. bulk RNA sequencing, single cell RNA sequencing, spatial transcriptomics) Provide solutions to problems of moderate complexity that require creative use of established and/or innovative methods. Collaborate with colleagues for experimental design, assay performance, data acquisition and analysis. Perform technical laboratory procedures, where attention to detail, effective troubleshooting skills and good judgment are required. Maintain an accurate and detailed laboratory notebook and maintain complete records of experiments. Contribute to basic lab maintenance (restocking, waste removal, organization etc.) Participate in preparing for annual safety inspections and maintaining a safe laboratory environment. Maintain a clean and safe laboratory work area; perform daily maintenance, clean up, and workspace organization within assigned work areas. Perform other duties as assigned. Additional duties at the SES.2 level: Analyze current process procedures and provide feedback for the optimization and improvement of workflow. Perform quality control and maintenance of laboratory equipment. Provide occasional training on laboratory procedures to other employees. Offer feedback, identify areas of improvement and efficiency on laboratory protocols. Attend and present technical status reports at meetings. Ability to secure and maintain a U.S. DOE Q-level security clearance which requires U.S. Citizenship. Bachelor's Degree in Neuroscience, Biology, Biochemistry or related field or the equivalent combination of education and related experience. Fundamental knowledge of and experience with sterile techniques, culturing and maintenance of tissue cultures, and media preparation. Fundalmental knowledge of cellular and biochemical techniques (electrophysiology, optical microscopy, immunostaining). Fundamental understanding of multiomic techniques (transcriptomics, proteomics) Ability to use scientific instruments and operate standard equipment in routine assignments. Ability to follow directions and standard written laboratory protocols. Basic computer skills, including experience with standard software and database programs such Excel, Word, and PowerPoint. Ability to perform basic laboratory maintenance (restocking, waste removal, organization etc.). Sufficient written, verbal communication and interpersonal skills necessary to deliver presentations, prepare written reports and to interact with a diverse set of scientists, engineers, and other technical and administrative staff. Work effectively in a fast-paced, multidisciplinary environment both independently and as a team with a diverse set of scientists, administrative, and other technical staff. Effective problem-solving skills to implement solutions of limited complexity. Ability to work weekends. Qualifications at the SES.2 level: MA/MS in Neuroscience, Biology, Biochemistry or related field or the equivalent combination of education and related experience Comprehensive knowledge of, and experience, with multi-omics sample preparation and analysis. Ability to carry out experiments for primary rat and human cells in Biosafety Level 2 laboratory. Qualifications we desire: Ability to work and troubleshoot independently. Ability to be organized, work with large teams and communicate effectively. Data analysis including R and statistics.

Livermore, California, We are seeking a Postdoctoral Researcher to develop resonance ionization mass spectrometry (RIMS) including establishing a new RIMS instrument for nuclear forensics and cosmochemistry. You will use your problem-solving skills to find solutions to challenging questions, as well as build and tinker with complex instruments. In addition to RIMS, we have a suite of state-of-the-art mass spectrometers and microanalytical instruments such as SIMS, SEM, EPMA that are available for your independent research. The LLNL RIMS lab is part of a new NASA Planetary Science Enabling Facility that hosts researchers analyzing extraterrestrial materials such as meteorites. This position is in the Trace Isotope and Element Signatures Group in the Nuclear and Chemical Sciences Division, within the Physical and Life Sciences Directorate. You will Work with a team to establish and commission a new generation of RIMS instruments. Develop and apply new methods of isotopic and elemental analysis for application to nuclear forensics and cosmochemistry. Find and develop new applications for RIMS; for example laser spectroscopy, environmental chemistry, isotope geology. Conduct analysis of real-world and simulated materials to demonstrate new capabilities, communicate those results in written reports and presentations. Help to improve and maintain current and future RIMS instruments and laser systems. Publish research results in peer-reviewed scientific or technical journals. Present results at external conferences, seminars, and/or technical meetings. Perform other duties as assigned. Ability to secure and maintain a U.S. DOE Q-level security clearance, which requires U.S. Citizenship. PhD in physical chemistry, experimental physics, analytical chemistry, or related field. Experience in one or more of the following: laser systems, ion sputtering and/or laser ablation, ion optical systems, and data acquisition systems. Experience in designing and/or building laboratory equipment. Familiarity with the field of mass spectrometry and understanding of the current state of knowledge in this field. Ability to develop independent research projects as demonstrated through publication of peer-reviewed literature. Ability as an innovative experimentalist with experience in experimental design, techniques, and execution, and the ability to work independently as well as in multidisciplinary research teams. Proficient written and verbal communication skills necessary to deliver presentations and prepare written publications, and reports. Qualifications We Desire Experience preparing and analyzing environmental and anthropogenic samples for radionuclides and stable isotopes ranging in concentrations from trace to high-level. Publication record in peer-reviewed literature with experience presenting research results to a large audience. Experience in statistical analysis applied to uncertainty quantification. Experience programming in Python or a similar environment for hardware control, data acquisition, or data analysis.

Huntsville, Alabama, NASA’s George C. Marshall Space Flight Center (MSFC) X-Ray Group in the Astrophysics Branch of the Science and Technology Office plans to hire an early- and mid/late-career Permanent-Hire research astrophysicists. Successful candidates are expected to conduct an independent program in the research, development, and testing of the next generation of X-ray optics and instrumentation, and to lead or support a thriving high-energy astrophysics research and analysis program. The X-ray Group is currently seeking declarations of interest via a submitted letter of interest and CV (see below).  The X-Ray Astronomy Group has a long and rich history supporting mission development and implementation. Key missions that the Group is actively involved in include Chandra, SRG-ART – X-ray Concentrator (ART - XC), and the Imaging X-ray Polarimetry Explorer (IXPE). As NASA’s premiere Center for the development and test of full-shell X-ray optics, the Group is currently engaged in the development of X-ray optics for future strategic missions, including the next Great Observatory for X-ray Astronomy. MSFC’s facilities to support this work are substantial and include state of the art polishing machines, X-ray sources, detector systems, precision vacuum stages, coating chambers, and precision metrology instrumentation. MSFC is also home to two world-class X-ray Beamlines: the 500 meter X-ray and Cryogenic Facility (XRCF) and the MSFC 100-m X-ray Beamline that have been used for calibration of multiple X-ray and normal-incidence mirrors and telescope systems, including Chandra and JWST.  These are permanent civil servant positions. US Citizenship is required. Once the posting is open, applicants will apply through https://www.USAJOBS.gov . The delay between this request and the job posting is to allow for adequate community response. Enabling USAJOB alerts using the features of the website can notify interested candidates of the job opportunity opening. It is strongly suggested that the submitted application map closely to the position requirements. Interested Applicants should send a letter stating their interest and a CV directed to Jessica Gaskin, X-Ray Group Astronomy Lead, [email protected] and ST12 Branch Chief, Katherine Chavis, [email protected] . Those who respond will receive specific notification when the respective USAJOBS opportunity opens. Note that these documents are not required to apply for the job, but are strongly encouraged . There are expected to be two civil service positions; an early/mid-career GS13/14 and mid/late-career GS14/15.