Latest Jobs from Physics Today

Translational Immunology - Academic Graduate Appointee | Lawrence Livermore National Laboratory

6 hours 32 minutes ago
Livermore, California, We have one opening for an Academic Graduate Appointee to support projects focused on developing novel nanoparticle-based vaccines against various bacterial and viral pathogens. The candidate will work in a highly integrated environment as part of a multi-disciplinary team to develop, optimize, characterize, and validate nanoparticle-based vaccine formulations. This position will include the production and characterization of protein antigens and nanoparticle constituents. This position is in the Biology and Biotechnology Division, Translational Immunology Group. In this role you will: Express, purify, and characterize proteins of high purity required for in vivo applications. Prepare, purify, and characterize nanoparticle platforms tailored for different vaccine formulations and vaccination routes. Use instrumentation to characterize purity, size, and homogeneity of biomolecules. Support routine immunological assays to assess vaccine formulations. Keep an accurate and detailed laboratory notebook and maintain complete records of experiments. Contribute to general lab maintenance, management of waste streams, and ordering/inventory of lab supplies. Compile data and protocols in Microsoft Office programs (Excel, Word, PowerPoint). Perform all assignments in accordance with ES&H, security, and business practice requirements and policies. Perform duties as assigned. B.S. or B.A. in biological sciences or equivalent course work (within two years of application). Experience with aseptic technique, microbial cultures, and protein purification. Interpersonal and communication skills to effectively work in a team environment with a diverse technical staff. Strong attention to detail and ability to follow standard laboratory protocols and ES&H safety procedures. Experience using personal computers, Word, Excel, and PowerPoint applications. Qualifications we desire: Experience with routine laboratory processes, including preparation of buffers Experience working with gel electrophoresis, western blot, and other common molecular biology techniques. Experience with DNA extraction including minipreps, maxipreps, gel extraction, and PCR purification. Experience with culturing bacteria, including transformation and plating. Experience with liquid chromatography instrumentation. Experience with handling and characterizing proteins.

Neuroscientist | Lawrence Livermore National Laboratory

6 hours 32 minutes ago
Livermore, California, NOTE: This is a flexible term position dependent on project funding. Current funding is expected for at least 2 years. The Bioscience and Biotechnology division within Physical and Life Sciences at LLNL is seeking to fill a position for a dedicated and hardworking Research Scientist with a background in Neuroscience/Neurobiology with demonstrated experience in behavioral assessments, electrophysiology and other advanced in vivo experimentation approaches. In this position, you will direct and conduct advanced animal biology research, contributing to our understanding of the brain for mission relevant programs. Your role will involve working on defined research projects, where you will be expected to demonstrate initiative, resourcefulness, and a keen attention to detail within a multidisciplinary team of scientists. This position is in the Animal Care Facility Group in the Biosciences and Biotechnology Division. In this role you will: Lead and conduct in vivo experiments that include rat models Collaborate with other scientists for in vivo experiments including behavioral assays/analyses Utilize advanced neurobiology techniques to investigate and understand mechanisms of brain injury/repair Evaluate large data sets to refine, inform, and design subsequent experiments. Conduct literature reviews on state-of-the-art approaches relevant to the problem being addressed. Train and mentor early career and technician level staff Collaborate and interact with inter-organizational contacts and/or external customers. Prepare and present technical reports Additional duties at the SES.3 level: Analyze current process procedures and provide feedback for the optimization and improvement of workflow. Perform quality control and maintenance of laboratory equipment. Provide occasional training on laboratory procedures to other employees. Offer feedback, identify areas of improvement and efficiency on laboratory protocols. Attend and present technical status reports at meetings. Perform other duties as assigned. Ability to secure and maintain a U.S. DOE Q-level security clearance which requires U.S. Citizenship. M.S. in Neuroscience or related field, or the equivalent combination of education and related experience. Proficient experience with rat behavior and physiology techniques, including electrophysiology, behavioral testing and apparatus training and optimization. Proficiency in statistical data analyses. Comprehensive experience with ex vivo sample collection and preparation for molecular biology, histology, or -omics analyses. Practical experience with animal handling and behavioral testing Proficient with Microsoft Office applications and comprehensive ability to learn new software. Proficiency with surgical practices and histology AAALAS certification at LAT, LATG or CMAR level desirable. Qualifications at the SES.3 level: Ph.D. in Neuroscience or related field, or the equivalent combination of education and related experience. Experience in a fast-paced environment and able to work both independently and as a team member with a diverse set of scientists, engineers, and other technical and administrative staff. Significant experience with in vivo behavioral assessments. Lead junior team members with coaching, mentoring, and training Conduct experiments independently, with troubleshooting and optimization as necessary Be responsible for experimental outcomes and report to project leads

Computational Physicist | Lawrence Livermore National Laboratory

6 hours 32 minutes ago
Livermore, California, We have an opening for a Computational Scientist to work on next-generation fissile materials production modeling and simulation using state-of-the-art adaptive computing technologies to integrate models with advanced data analytics and machine learning. You will develop models to enable simulation of proliferation processes and accurate assessment of possible proliferation activities. This position is in the Applied Physics Section in the Physics Division. Depending on your assignment, this position may offer a hybrid schedule, blending in-person and virtual presence. You may have the flexibility to work from home one or more days per week. You will Learn underlying physics and operational procedure of existing suite of computational models for fissile-materials production. Enhance existing and develop new computational models for processes and components associated with fissile materials production using a new adaptive computing environment, coupled to high-performance computing capabilities, as needed. Use hierarchy of complex computational models to provide expert input and technical advice to national security nuclear analysts. Apply machine learning and statistical analysis to computer simulation outputs to couple simulation codes, to perform and analyze large-scale statistical studies, and to generate synthetic machine-learning models. Maintain an awareness of technical literature in assigned areas. Periodically, prepare written analyses and verbal briefings that capture and communicate research results. Publish research results in technical and/or peer-reviewed scientific journals, and present results at technical meetings and/or external conferences. Occasional travel as necessary to interact with sponsors and collaborators. Perform other duties as assigned. Ability to secure and maintain a U.S. DOE Q/SCI-level security clearance which requires U.S. citizenship. PhD in Nuclear Engineering, Physics, Computational Science, or related field, or the equivalent combination of education and relevant experience. Significant experience developing complex computational physics codes. Advanced knowledge and significant experience in developing computational models and simulations. Significant experience with artificial intelligence, machine learning, and/or data analytics. Significant experience authoring technical and scientific reports, publications and delivering scientific presentations. Advanced verbal and written communication skills necessary to effectively collaborate in a team environment and present and explain technical information and provide advice to management and external sponsors. Ability to travel off-site for sponsor and collaborator interaction. Qualifications We Desire Experience with adaptive computation environments and/or high-performance computing. Advanced knowledge and significant experience with the scientific and technological issues associated with national security in one or more of the following areas: nuclear fuel cycle, advanced technology/process model development, isotope production, data analytics, fluid flow, industrial chemical facilities, foreign weapon programs, or related emerging technologies.

Structural Vaccinology - Postdoctoral Researcher | Lawrence Livermore National Laboratory

6 hours 32 minutes ago
Livermore, California, NOTE: This is a two-year Postdoctoral appointment with the possibility of extension to a maximum of three years. We are seeking a highly motivated P ostdoctoral Researcher to join our team in the field of structural vaccinology and computational immunology. The successful candidate will work at the nexus of physics-based modeling and machine learning techniques and apply state-of-the-art experimental evaluations. You will work in an interdisciplinary team that includes computational structural biologists, infectious disease biologists, immunologists, engineers, and others to create a novel capability for designing broadly protective vaccine antigens. We offer a stimulating and inclusive work environment that fosters innovation and encourages professional growth. Join us in our mission to advance vaccine development and make a positive impact on global health. In this role, you will: Conduct advanced independent research to design and construct vaccine candidates using both experimental and computational approaches Employ a variety of structural biology techniques, including X-ray crystallography and cryo-electron microscopy, to determine the 3D structures of vaccine candidates and their interactions with the immune system Use physics-based modeling, simulation, and machine learning techniques to predict protein-protein interactions, protein stability, and other biophysical properties Use high-throughput and automated protein expression systems and characterization assays to design and test vaccine immunogens in vitro Develop collaboration with a multi-disciplinary team of computational scientists, structural biologists, engineers, and immunologists to integrate computational models with experimental data internally and with external partners in academia, industry, and other national laboratories Publish research results in peer-reviewed scientific or technical journals and present results at external conferences, seminars, and/or technical meeting. Work with other scientists to write proposals and expand our program into new areas aligned with your expertise and interests PhD in Structural biology, biochemistry, biophysics, computer science, computational biology, computational physics, computational chemistry or equivalent combination of education and related experience. Experience with protein expression, purification, and structural biology techniques Advanced knowledge and significant experience in vaccine design and immunology Ability to work independently on defined research projects, as well as a member of a large team. Ability to develop independent research projects as demonstrated through publication of peer-reviewed manuscripts Ability to travel, as necessary, to interact with sponsors, customers and collaborators Advanced written, verbal communication and interpersonal skills necessary to deliver presentations, prepare written reports and to interact with a diverse set of scientists, engineers, and other technical and administrative staff. Qualifications We Desire: Experience in collaborating with experimental and computational biologists as well as understanding and using experimental data in combination with computational research Experience with computational modeling and simulation of protein structure and with other computational tools for describing or predicting biophysical properties of proteins Experience in developing and training machine-learning based models in high-performance computing systems. Experience computing binding affinity, stability and/or other metrics using scoring functions like Rosetta Demonstrated ability to manage and prioritize multiple tasks and deliver high-quality results within deadlines

Physics Division Undergraduate Intern - Fall 2024 | Lawrence Livermore National Laboratory

6 hours 32 minutes ago
Livermore, California, We have multiple openings for undergraduate students to engage in practical research experience to further their educational goals. Opportunities include participation in projects led by LLNL scientists in research areas including: Applied Physics (Optical and X-Ray Imaging, Astrophysics and Planetary Science (laboratory-based and observational), Space Science Vehicles & Sensors); Condensed Matter Physics (Theory, Modeling & Simulation, Experimental Static & Dynamic High Pressure Physics, Quantum Computing & Sensing); High Energy Density Physics (Experimental Laser and Magnetically-driven compression, Theory, Modeling and Simulation of HED states); and Plasma and Fusion Energy Science (Fusion Energy Modeling & Simulation, Tokamak development experiments & diagnostics, Applications of Plasma Science). These positions are in the Physical and Life Sciences Directorate, Physics Division. Applications for Physics Division Fall 2024 internships are due by COB October 31, 2024. You will Work with scientists conducting research in experiments, theory or modeling simulation, and materials modelling. Conduct research in assigned areas under close direction and supervision. Perform scientific assignments at an appropriate level of complexity and work collaboratively on scientific research and development projects. Analyze results and provide weekly updates. Present work through presentations and/or poster sessions. Perform other duties as assigned. Must be a continuing student in good standing at an accredited institution pursuing a bachelor's degree in Physics or a related field. Demonstrated academic achievement in Physics or related field. Ability to apply basic physics principles to solve technical problems. Demonstrated effective communication skills. Ability to present and communicate concepts and ideas. Knowledge in Materials Science/Physics/Applied Mathematics/Applied Sciences. Familiarity with modern computer-based data analysis approaches, summarizing and presenting results. Ability to work in a team environment.

Machine Learning for Shock Hydrodynamics - Postdoctoral Researcher | Lawrence Livermore National Laboratory

6 hours 32 minutes ago
Livermore, California, We have an opening for a Postdoctoral Researcher with a research track-record in physical sciences with interest in career growth in optimization, machine learning, automatic differentiation, and computational inverse problems. The position combines physics and optimization experience to promote scientific and programmatic growth within the strengths of the group. Specific investigations include combining complex hydrodynamics models with computational approaches to facilitate large-scale investigations and machine learning-based design optimization. You will actively participate in research that includes Richtmyer-Meshkov and other instabilities; model development describing fundamental, dynamic processes; and multi-scale and continuum computational investigations of the effect of such processes on bulk material behavior. This position is in the Material Dynamics and Kinetics group within the Energetic Materials & Design (EMD) section of the Materials Science Division, supporting the Energetic Materials Center (EMC). This position requires full-time on-site presence due to the nature of the work. You will Develop world-leading ML and optimization techniques to study problems in physics. Conduct research to understand the fundamental phenomena that affect or control dynamic materials properties, including material instabilities, plasticity/strength, porosity, turbulence, and phase transformations kinetics. Contribute to the conception, design, and execution of research to address defined problems. Engage in scientific and programmatic connections with Laboratory-wide efforts and customers, through the promotion of research advancements that tackle Laboratory missions. Develop understanding of customer needs in order to contribute to development and sustenance of funding support for new and existing research both within and outside of LLNL. Maintain and establish laboratory protocols. Document research; publish papers in peer-reviewed journals, and present results within the DOE community and at conferences. Perform other duties as assigned. PhD in Chemistry, Materials Science, Engineering, Mathematics, Physics or a related field. Experience in one or more of the following areas: Computational multiscale modeling, energetic materials, molecular dynamics, multi-physics, hydrodynamics, non-equilibrium statistical physics, highly dynamic high-pressure physics, optimization, machine learning, or computational inverse problems. Experience as an innovative computational scientist with experience in dynamic materials phenomena or optimization techniques, and documented track record of success. Ability to represent and document research through programmatic and scientific presentations and publications or technical reports of results. Proficient verbal and written communication skills as reflected in effective presentations at seminars, meetings and/or teaching lectures. Initiative and interpersonal skills with desire and ability to work in a collaborative environment. Qualifications We Desire Experience working with or implementing world-class computational physics and hydrodynamic codes. Knowledge in fluid dynamics and condensed matter physics. Established record of conceiving and executing pioneering multidisciplinary projects.

Laser-Material Interactions - Postdoctoral Researcher | Lawrence Livermore National Laboratory

6 hours 32 minutes ago
Livermore, California, We have an opening for a Postdoctoral Researcher to independently work on laser-material interactions with emphasis on laser ablation, laser shock physics, and dynamic compression of material. Particular interest will be shown to candidates with hands-on laboratory experience, experience in developing diagnostics for laser shock physics, and advanced analysis of data to validate simulation codes in laser induced shock generation. This position is in the Laser Material Interaction Science group of the Materials Science Division. In this role you will Conduct advanced research related to laser compression of materials. Develop and implement novel diagnostics (i.e. laser velocimetry) to study laser shock physics. Research new tamper materials to enhance laser impulse through materials. Organize, analyze, and present data from research. Convey capabilities and new opportunities to DOE and internal sponsors. Develop and present written analyses and verbal briefings that capture and communicate research results as well as periodic progress reports. Publish research results in peer-reviewed scientific or technical journals and present results at external conferences, seminars and/or technical meetings. Perform other duties as assigned. Ability to secure and maintain a U.S. DOE Q-level security clearance which requires U.S. citizenship. Ph.D. Physics, Material Science, Chemistry, Mechanical Engineering, Chemical Engineering, or related field. Hands on experience in laser induced shock compression of metals. Experience with various laser (CW, ns, ps, and fs), especially high energy short pulse laser systems. Experience working in large laser user facilities. Knowledgeable of laser material interaction at short timescales. Knowledgeable of x-ray effects in materials. Ability to perform as an innovative experimentalist with a broad range of experience in experimental design, techniques, execution, and analysis, and the ability to think broadly and devise innovative solutions to problems to accomplish objectives.. Proficient written and verbal communication skills necessary to deliver presentations and prepare written reports, explain technical information, and provide advice to management. Initiative and interpersonal skills including the ability to work both as part of a collaborative, multi-disciplinary team, as well as the ability to produce independent, original work. Qualifications We Desire Experience in using class 4 lasers, optics layout, and engineering. Experience with hydrodynamic codes to support experimental efforts.

Senior Design Physicist | Lawrence Livermore National Laboratory

6 hours 32 minutes ago
Livermore, California, We have multiple openings for Design Physicists who are exceptional physical scientists and engineers with backgrounds in fields such as plasma physics, radiation transport, atomic physics, nuclear physics, physical chemistry, condensed matter physics, computational physics, or hydrodynamics. Our national-security mission encompasses aspects of computational, theoretical, and experimental physics associated with the complex processes of nuclear explosives. Under limited direction, you will be responsible for advancing our understanding and developing methodologies for important national-security challenges. This position is in the Design Physics Division within the Strategic Deterrence Directorate. These positions may offer a hybrid schedule, blending in-person and virtual presence. You may have the flexibility to work from home one or more days per week. These positions will be filled at either level based on knowledge and related experience as assessed by the hiring team. Additional job responsibilities (outlined below) will be assigned if hired at the higher level. In this role, you will Design and provide analysis of complex experiments exploring the physics of nuclear explosives. Simulate weapons phenomena and perform weapons assessment and certification tasks using physical models in computer codes. Participate in the assessment of foreign nuclear weapon systems. Present and disseminate research results at scientific conferences and in peer-reviewed publications, in both open and classified environments, internal and external to LLNL. Positively represent the Program and Laboratory demonstrating advanced verbal and written skills. Responsibilities may also include interacting with external stakeholders, both at NNSA and across the broader interagency, via offsite assignments. Develop expertise in interrelated fields of physics important to weapons assessment and certification. Lead independent work conducting applied physics research. Lead and mentor staff as part of a multidisciplinary team. Lead top quality research in relevant areas of physics and engineering. Problem-solve and make decisions necessary to independently address challenging problems. Recognize and support plans to promote and foster a culture of inclusion, diversity, equity, and accountability within the workplace. Perform other duties as assigned. Additional job responsibilities at the SES.4 Level Assess the highly complex physics interactions that take place in a nuclear explosion. Design and provide in depth analysis of experiments exploring the physics of nuclear explosives. Define and implement stockpile stewardship for specific weapons systems. Simulate weapons phenomena and perform highly advanced weapons assessment and certification tasks using physical models in computer codes. Ability to maintain a U.S. DOE Q-level security which requires U.S. citizenship. Master's degree in physics, engineering, or related field or equivalent combination of education and related experience. Significant experience conducting applied physics research. Demonstrated record of completing outstanding research in relevant areas of physics and engineering. Significant experience with advanced computer-based design and analysis of experiments. Demonstrated aptitude for mastering new fields of physics; a record of creativity, physical insight, and breadth of understanding in advanced applications of complex physical processes. Significant experience in using advanced computational facilities for applied physics analysis. Advanced verbal and written communication and presentation skills necessary to author advanced technical and scientific reports, publications, invited papers, and to deliver scientific presentations. Significant experience working effectively independently and in a multidisciplinary, team-research environment. Demonstrated self-motivation and initiative in addressing challenging problems. Additional qualifications at the SES.4 Level Substantial experience presenting and disseminate highly advanced research results at scientific conferences and peer-reviewed publications, in open and classified environments, internal and external to LLNL. Substantial experience communicating results of work with external sponsors. Substantial experience developing innovative methods to expand knowledge of interrelated fields of highly advanced physics important to weapons assessment and certification. Substantial experience setting specific strategies and/or directing multi-disciplinary teams to achieve program goals. Qualifications we desire Demonstrated subject matter expert knowledgeable of highly advanced concepts to include experience and ability to lead independent work conducting applied physics research in one or more of the following fields: plasma physics, radiation transport, atomic physics, nuclear physics, and hydrodynamics. Significant experience with highly advanced computer-based design and analysis of highly complex experiments. Extensive experience at the expert level in the development of principles, theories, concepts, and techniques relevant to applied physics research. Demonstrated ability/commitment to promote and value inclusion, diversity, equity and accountability principles in the workplace. Please include a personalized cover letter with your application, highlighting your qualifications and why you're interested in this position.

Inertial Confinement Fusion Physicist | Lawrence Livermore National Laboratory

6 hours 32 minutes ago
Livermore, California, We have multiple openings for Inertial Confinement Fusion Physicists to become part of the team working on the grand challenge of achieving thermonuclear ignition on the National Ignition Facility (NIF). This research requires working closely with individuals from other disciplines, such as laser experimentalists, laser scientists, target fabrication specialists and NIF Project scientists and engineers, as well as other target designers and theorists. These positions are in the Design Physics Division within the Strategic Deterrence (SD) Directorate. These positions may offer a hybrid schedule, blending in-person and virtual presence. You may have the flexibility to work from home one or more days per week. These positions will be filled at either level based on knowledge and related experience as assessed by the hiring team. Additional job responsibilities (outlined below) will be assigned if hired at the higher level. In this role you will Plan, analyze and interpret NIF laser experiments in support of the effort to achieve ignition on NIF principally with large computer codes, but also with analytic modeling. Perform computational and theoretical analyses that extrapolate our current understanding of ignition related physics to NIF and beyond. Successfully work as part of an interdisciplinary team on ICF project activities. Present research results in scientific meetings, peer reviews, and publications. Responsibilities may also include interacting with external stakeholders, both at NNSA and across the broader interagency, via offsite assignments. Promote and support plans to promote diversity, equity, and inclusion within the program. Perform other duties as assigned. Additional responsibilities at the SES.3 Level Independently develop and/or provide in depth analysis of NIF laser experiments in support of the effort to achieve ignition on NIF principally with large computer codes, but also with analytic modeling where complex problems may not be well defined. Work as technical expert on multidisciplinary team. Ability to maintain a U.S. DOE Q-level security which requires U.S. citizenship. PhD in physics or related field, or the equivalent combination of education and related experience. Comprehensive knowledge of plasma physics, hydrodynamics, or astrophysics. Experience in computational modeling of complex systems. Experience developing creative solutions to complex problems. Demonstrated ability to deliver a high quality, polished product in a timely manner. Proficient written and verbal communication skills as demonstrated by a record of publications, invited papers, or teaching experience. Demonstrated ability to interact effectively in an interdisciplinary team of scientists as well as independently. Additional qualifications at the SES.3 Level Advanced knowledge of physics, plasma physics, hydrodynamics, or astrophysics or a related field. Experience leading and mentoring as part of a multidisciplinary team. Demonstrated record of completing and/or leading top quality research in relevant areas of physics and engineering. Qualifications We Desire Experience with the use of large two and three-dimensional computer codes. Demonstrated ability/commitment to valuing diversity, equity, and inclusion principles in the workplace. Please include a personalized cover letter with your application, highlighting your qualifications and why you're interested in this position.

Senior Antibody Design Lead | Lawrence Livermore National Laboratory

6 hours 32 minutes ago
Livermore, California, We have an opening for a Senior Antibody Design Lead to join ongoing projects developing innovative biologics against infectious diseases. You will be responsible for overseeing the development of antibody drug products from concept to transition to commercial partners. You will lead activities conducted by cross-functional teams that include exploring technical feasibility, developing strategy, performing computational design, and performing laboratory validation. You will have extensive experience with infectious disease and managing translational research processes aimed at preparing biologics for pre-clinical trials. This position is in the Microbiology/Immunology group of the Biosciences and Biotechnology Division. This position will be filled at either the SES.4 or the SES.5 level based on knowledge and related experience as assessed by the responsibilities (outlined below) will be assigned if hired at the higher level. You will Lead the development of antibody drug products. This includes coordinating and leading subject matter experts to assist in exploring technical feasibility and strategic aims of potential new antibody products, working with team leads responsible for computational antibody design, and working with teams leads responsible for antibody production and characterization, Collaborate with cross-functional teams, including R&D efforts on new assay development and new laboratory technologies. Collaborate with external partners that provide reagents, assays, and/or protein production capabilities. Develop product development strategies, including working with project manager to define and track highly complex multi-year project plans, timelines, and budgets. Prepare scientific reports summarizing results from highly complex research activities performed onsite and with partner organizations. Work with laboratory director to oversee recombinant mammalian and bacterial protein expression and purification. Interface with computational teams performing computational design. Develop and maintain relationships with external partners and collaborators. Stay up-to-date with industry trends and advancements in antibody technology. Perform other duties as assigned. Additional job responsibilities at the SES.5 level Anticipate project shortcomings in advance and direct resources to develop effective solutions to improve efficiency in key areas relevant antibody design and discovery. Initiate and/or lead collaborative projects requiring involvement of broader scientific community external to LLNL. Lead multi-location research teams, including summarizing research results in peer-reviewed journals, Ph.D. in Molecular Biology, Cell Biology, or related field the equivalent combination of education and related experience. Highly advanced experience in antibody product development for infectious diseases, including experience in antibody generation and development, biomarker development, assay design, and antibody purification Substantial knowledge of cell biology, molecular biology, and biotechnology Expert with laboratory management, including molecular biology and cell biology Substantial experience with recombinant mammalian and bacterial protein expression and purification Expert leadership, communication, and project management skills. Significant experience developing and managing workflows for high throughput antibody production and screening platforms. Expert written, verbal communication and interpersonal skills necessary to deliver presentations, prepare written reports and to interact with a diverse set of scientists, engineers, and other technical and administrative staff. Additional qualifications at the SES.5 level: Significant experience with regulatory submissions and compliance Proven track record of leading cross-functional teams and developing successful product development strategies Expertise in library display technologies for high throughput screening, e.g., mammalian cell-based expression/display, yeast display, and/or other platforms. Extensive experience with additional protein purification and characterization techniques. Experience developing and managing workflows for large-scale (batch) antibody production, purification, and characterization. Experience with automated workflows and automation platforms (e.g., Hamilton robotic liquid handlers)

Computational Physicist | Lawrence Livermore National Laboratory

6 hours 32 minutes ago
Livermore, California, We have multiple openings for Computational Physicists aiming to improve national security through the development of simulation codes for world class supercomputing architectures. You will collaborate as part of an interdisciplinary team in advancing state-of-the-art physics simulation capabilities. Applications may include inertial confinement fusion, high-energy density physics, nuclear/conventional weapons, or nuclear counterterrorism. Our projects span the range from smaller, focused research codes/modules to multi-physics, multi-application production codes. This position is in the Design Physics Division within the Strategic Deterrence Directorate. These positions may offer a hybrid schedule, blending in-person and virtual presence. You may have the flexibility to work from home one or more days per week. These positions will be filled at either level based on knowledge and related experience as assessed by the hiring team. Additional job responsibilities (outlined below) will be assigned if hired at the higher level. You will Build simulation tools using modern software practices as part of a team. Develop models and algorithms to support physics capabilities for a diverse application space. Support users of your simulation tools. Share results through conferences, reports/publications, and potential interactions with collaborators. Recognize and support plans to promote and foster a culture of inclusion, diversity, equity, and accountability within the workplace. Perform other tasks as assigned. Additional responsibilities at the mid-career (SES.3) level Develop and critically assess physics capabilities to support applications requiring advanced simulation tools to solve complex problems. Collaborate as a technical expert on multidisciplinary teams. Set specific technical strategies to achieve project goals. Ability to secure and maintain a U.S. DOE Q-level security clearance which requires U.S. citizenship. PhD or equivalent level of proficiency in physics, mathematics, engineering, or related field. Proficiency in developing scientific applications in Python, C/C++, or FORTRAN. Proficiency in converting theory into computational models, implementing computational models, or evaluating computational algorithms and methods for their applicability. Effective verbal and written communication skills and experience authoring high-quality reports/publications and delivering effective technical presentations. Additional qualifications at the mid-career (SES.3) level Advanced knowledge of physics, mathematics, engineering, or a related field. Significant professional programming experience. Experience in leading, mentoring, and/or collaborating within teams. Advanced verbal and written communication skills and a demonstrated record of delivering top-quality research in relevant areas of science and engineering. Qualifications We Desire Expertise in one or more science disciplines, such as shock hydrodynamics, solid/fluid mechanics, materials science, particle transport, radiation transport, nuclear physics, plasma physics, or physical chemistry. Proficiency in developing and supporting multi-dimensional numerical simulation. Proficiency in developing scientific simulations for high-performance and/or heterogeneous computing systems (e.g., use of MPI, OpenMP, Cuda/HIP, or other HPC technologies). Proficiency in developing advanced technical solutions (e.g., numerical algorithms). Proficiency in working in a multidisciplinary team-research environment, demonstrating creativity and initiative in addressing challenging problems. Demonstrated ability/commitment to promote and value inclusion, diversity, equity, and accountability principles in the workplace. Please include a personalized cover letter with your application, highlighting your qualifications and why you're interested in this position.

Design Physicist | Lawrence Livermore National Laboratory

6 hours 32 minutes ago
Livermore, California, We are seeking exceptional Physical Scientists and Engineers with backgrounds in fields such as plasma physics, radiation transport, atomic physics, nuclear physics, physical chemistry, condensed matter physics, computational physics, or hydrodynamics. Our national-security mission encompasses aspects of computational, theoretical, and experimental physics associated with the complex processes of nuclear explosives. Under limited direction, you will be responsible for advancing our understanding and developing methodologies for important national-security challenges. This position is in the Design Physics Division within the Strategic Deterrence Directorate. These positions may offer a hybrid schedule, blending in-person and virtual presence. You may have the flexibility to work from home one or more days per week. These positions will be filled at either level based on knowledge and related experience as assessed by the hiring team. Additional job responsibilities (outlined below) will be assigned if hired at the higher level. You will Assess the complex physics interactions that take place in nuclear explosion. Design and provide analysis of experiments exploring the physics of nuclear explosives. Simulate weapons phenomena and perform weapons assessment and certification tasks using physical models in computer codes. Define and implement stockpile stewardship for specific weapons systems. Present and disseminate research results at scientific conferences and in peer-reviewed publications, in both open and classified environments, internal and external to LLNL. Responsibilities may also include interacting with external stakeholders, both at DOE/NNSA and across the broader interagency, as well as via offsite assignments. Develop expertise in interrelated fields of physics important to weapons assessment and certification. Travel minimally or substantially based on needs of projects. Recognize and support plans to promote and foster a culture of inclusion, diversity, equity, and accountability within the workplace. Perform other duties as assigned. Additional job responsibilities at the SES.3 Level Independently develop, assess and provide in depth analysis of the complex physics interactions that take place in nuclear explosion where problems may not be well defined. Work as technical expert on multidisciplinary team. Guide the analysis and lead the design of experiments exploring the physics of nuclear explosives. Ability to obtain and maintain a U.S. DOE Q-level security clearance which requires U.S. Citizenship. PhD in physics, engineering, or a related field or equivalent level of demonstrated knowledge. Demonstrated record of completing outstanding research in relevant areas of physics and engineering. Experience with computer-based design and analysis of experiments. Demonstrated aptitude for mastering new fields of physics; a record of creativity, physical insight, and breadth of understanding in applications of complex physical processes. Experience in using advanced computational facilities for applied physics analysis and conducting applied physics research. Proficient verbal and written communication and presentation skills necessary to author technical and scientific reports, publications, invited papers, and to deliver scientific presentations. Experience working effectively independently and in a multidisciplinary, team-research environment. Demonstrated self-motivation and initiative in addressing challenging problems. Additional qualifications at the SES.3 Level Advanced knowledge of physics, engineering, or a related field. Significant experience and ability to lead independent work conducting applied physics research. Demonstrated record of leading top quality research in relevant areas of physics and engineering. Qualifications we desire Demonstrated ability/commitment to promote and value inclusion, diversity, equity, and accountability principles in the workplace. Please include a personalized cover letter with your application, highlighting your qualifications and why you're interested in this position.

Senior Computational Physicist | Lawrence Livermore National Laboratory

6 hours 32 minutes ago
Livermore, California, We have openings for Computational Physicists to pursue challenges relevant to national security in the development of multi-physics simulation codes. Under consultative direction you will collaborate as part of an interdisciplinary code development team in advancing the state of the art in large-scale multi-physics simulation. The national security mission involves developing simulation capabilities for Stockpile Stewardship, nuclear counter-terrorism, conventional weapons, and high energy density physics experiments. The code development focus is on models and algorithms for use in high-performance computing on the latest large-scale parallel computing platforms. You will act as a scientific/technical leader as part of large projects/programs, contribute to the development of innovative principles and ideas, will play a role in attracting and retaining projects, programs, and funding due to degree of technical expertise. This position is in the Design Physics Division within the Strategic Deterrence Directorate. These positions may offer a hybrid schedule, blending in-person and virtual presence. You may have the flexibility to work from home one or more days per week. In this role, you will Develop algorithms and simulation tools to advance the state of the art in multi-physics simulation for a large variety of physical processes in 2D and 3D, where problems are not well defined. Independently develop and/or provide in-depth analysis of physics capabilities in support of a diverse user community using advanced simulation tools to solve highly complex problems that may not be well defined. Provide advanced technical support, informal training, and guidance to code users in the application of simulation tools developed. Collaborate in the development of simulation tools and direct/influence the strategy and technical direction of research activities as part of a multi-disciplinary team. Present and disseminate advanced research results at scientific conferences and in peer-reviewed publications, in both open and classified environments, internal and external to LLNL. Promote and support plans to promote diversity, equity, and inclusion within the program. Set broad technical strategies and/or direct multi-disciplinary teams to achieve program goals. Perform other duties as assigned. Ability to secure and maintain a U.S. DOE Q-level clearance which requires U.S. citizenship. PhD in one or more of these specialized fields: physics, mathematics, engineering, or related field or the equivalent combination of education and related experience. Subject matter expert knowledge of highly advanced concepts to include experience and ability to lead independent work in one or more science disciplines, such as shock hydrodynamics, fluid mechanics, material behavior, particle transport, radiation transport, plasma physics. Significant experience evaluating algorithms and methods for their fitness for a particular task, as well as developing and implementing new numerical algorithms. Significant experience developing and supporting and/or leading multi-dimensional numerical simulation and demonstrated analytical and conceptual skills and creativity. Advanced programming experience/fluency in Python, FORTRAN, C and/or C++ and significant experience developing and implementing algorithms for massively-parallel computer architectures. Significant experience working independently and in a team-research environment effectively. Significant experience at the expert level in the development of principles, theories, concepts, and techniques relevant to applied physics research and experience converting theory into models or algorithms appropriate for numerical simulation. Qualifications we desire Demonstrated experience implementing plans that promote and value inclusion, diversity, equity, and accountability principles in the workplace. Please include a personalized cover letter with your application, highlighting your qualifications and why you're interested in this position.

High Throughput Antibody Characterization Scientist | Lawrence Livermore National Laboratory

6 hours 32 minutes ago
Livermore, California, We have an opening for a Staff Scientist in our high throughput antibody production and characterization team. This exciting opportunity is ideal for an experienced bench scientist proficient in high throughput antibody characterization. You will be responsible for the development, implementation, and continuous optimization of automated high throughput screening platforms for the characterization of computationally designed therapeutic antibodies. Our team values scientific excellence, innovation, diverse perspectives, and collaboration. Join our dynamic team of scientists dedicated to advancing biotechnology and making a significant impact on drug discovery and development. You will Contribute to developing and implementing high throughput antibody characterization assays (e.g., BLI, SPR, capillary electrophoresis, DLS, DSF) Contribute to developing and implementing high throughput immunoassays (e.g., AlphaLISA, MSD, Gyros, Luminex, etc.) Analyze and interpret experimental data, troubleshoot technical issues, and propose innovative solutions Collaborate with cross-functional teams to support the generation of therapeutic antibodies for various drug discovery programs Maintain accurate and detailed laboratory records, write technical reports, and present findings to project teams and stakeholders Perform other duties as assigned B.S. degree or equivalent experience in biotechnology, biochemistry or a related scientific discipline Comprehensive hands-on experience in high throughput protein characterization techniques Proficiency with protein analytical techniques such as SDS-PAGE, Western blotting, ELISA or advanced immunoassay platforms (e.g., AlphaLISA, MSD, Gyrolab, Luminex) Familiarity with protein characterization assays (e.g., SPR, BLI, capillary electrophoresis, DLS, DSF) Experience using automated liquid handling systems and LIMS Demonstrate ability to work effectively in a team environment and collaborate with colleagues from diverse scientific backgrounds Strong organizational skills, attention to detail, and ability to multitask in a fast-paced research environment. Qualifications We Desire Design and execute experiments for high throughput antibody production and characterization using mammalian cell culture systems Increase efficiency of protein expression, purification, and characterization. Proficiency in molecular biology techniques, including gene cloning, transfection, and stable cell line generation Experience with antibody or other protein developability assessment.

Senior Design Physicist | Lawrence Livermore National Laboratory

6 hours 32 minutes ago
Livermore, California, We have openings for a Senior Design Physicist who is an exceptional physical scientist and engineer with a background in fields such as plasma physics, radiation transport, atomic physics, nuclear physics, physical chemistry, condensed matter physics, computational physics, or hydrodynamics. Our mission encompasses computational, theoretical, and experimental physics associated with the complex processes of national security challenges. These positions are in the Strategic Deterrence (SD) Directorate. Depending on your assignment, this position may offer a hybrid schedule, blending in-person and virtual presence. You may have the flexibility to work from home one or more days per week. These positions will be filled at either level based on knowledge and related experience as assessed by the hiring team. Additional job responsibilities (outlined below) will be assigned if hired. In this role, you will Assess, design and analyze complex physics interactions of relevance to our programs, creative/innovative methods. Present and disseminate innovative and highly complex research results at scientific conferences and peer-reviewed publications, in open and classified environments, internal and external to LLNL. Set broad research/project vision and strategy and influence technical direction for self and/or others. Perform all assignments in accordance with ES&H, security, and business practice requirements and policies. Serve as mentor to staff and other mentors across the organization. Serve as organization spokesperson by Laboratory management and/or external advisor by sponsors including scientific or technical committees. Recognize and support plans to promote and foster a culture of inclusion, diversity, equity, and accountability within the workplace. Ability to secure and maintain a U.S. DOE Q-level security clearance which requires U.S. citizenship. PhD in physics, engineering, or a related technical field or equivalent level of demonstrated knowledge. Expert knowledge of state-of-the-art concepts to include experience and ability to lead independent work conducting applied physics research in one or more of the following fields: plasma physics, radiation transport, atomic physics, nuclear physics, and hydrodynamics. Record of completing and/or leading outstanding research in relevant areas of physics and engineering. Extensive experience working effectively independently and in a multi-disciplinary, team-research environment. Expert problem-solving and decision-making skills necessary to independently address challenging problems. Nationally recognized expert knowledge in above-mentioned fields. Expert communicator to effectively present, explain, influence, and advise and represent the Program and Laboratory to senior management and external sponsors. Qualifications We Desire Demonstrated ability/commitment to promote and value inclusion, diversity, equity, and accountability principles in the workplace. Extensive expertise with computer-based design and analysis of experiments. Extensive experience at the expert level in the development of principles, theories, concepts, and techniques relevant to applied physics research.

Materials Science Division Graduate Student - Fall 2024 | Lawrence Livermore National Laboratory

6 hours 32 minutes ago
Livermore, California, We have multiple openings for graduate level students and students who have received a bachelor's or master's degree who will be given the opportunity to engage in practical research to further their educational goals. You will conduct research in the following scientific fields: organic/inorganic synthesis, analytical, computational, materials characterization, actinide materials, optical materials science; electrochemistry; materials chemistry and physics; computational chemistry and materials science; nanoscale materials synthesis and characterization and metallurgy. This position is in the Materials Science Division. In this role you will Work with scientists on projects involving hands-on work in a laboratory, computational, or data analysis. Conduct research in solid micromechanics in materials under limited direction and supervision. Contribute to developing integrated modeling capabilities for simulating micromechanical responses and fracture initiation in materials. Design and perform systematic computer simulations on LLNL supercomputers for understanding the effects of mechanical conditions on materials behavior. Perform technical assignments of a basic degree of complexity and providing advanced technical support to scientist in scientific research and development projects. Present work through presentations and/or poster sessions. Perform other duties as assigned. Must be a continuing college or university student in good standing at an accredited institution pursuing a graduate degree or has completed their bachelor's or master's degree in chemistry, materials sciences, computational chemistry, or a related field. Demonstrated academic achievement in chemistry, materials sciences, computational chemistry, or related field. Experience applying basic scientific principles to solve technical problems. Experience working with personal computers and familiarity with Microsoft Word, Excel and PowerPoint. Effective communication skills. Ability to present and communicate concepts and ideas. Ability to work in a team environment. Qualifications We Desire Broad knowledge of chemistry and materials. GPA of 3.0 or above.

Materials Science Division Graduate Intern - Fall 2024 | Lawrence Livermore National Laboratory

6 hours 32 minutes ago
Livermore, California, Job Description We have multiple openings for students who have received a bachelor's or master's degree to engage in practical research experience to further their educational goals. You will conduct research in the following scientific fields: organic/inorganic synthesis, analytical, computational, materials characterization, actinide materials, optical materials science; electrochemistry; materials chemistry and physics; computational chemistry and materials science; nanoscale materials synthesis and characterization and metallurgy. This position is in the Materials Science Division. In this role you will Work with scientists on projects involving hands-on work in a laboratory, computational, or data analysis. Conduct research in solid micromechanics in materials under limited direction and supervision. Contribute to developing integrated modeling capabilities for simulating micromechanical responses and fracture initiation in materials. Design and perform systematic computer simulations on LLNL supercomputers for understanding the effects of mechanical conditions on materials behavior. Perform technical assignments of a basic degree of complexity and providing advanced technical support to scientist in scientific research and development projects. Present work through presentations and/or poster sessions. Perform other duties as assigned. Must be a continuing college or university student in good standing at an accredited institution pursuing a graduate degree or has completed their bachelor's or master's degree in chemistry, materials sciences, computational chemistry, or a related field. Demonstrated academic achievement in chemistry, materials sciences, computational chemistry, or related field. Experience applying basic scientific principles to solve technical problems. Experience working with personal computers and familiarity with Microsoft Word, Excel and PowerPoint. Effective communication skills. Ability to present and communicate concepts and ideas. Ability to work in a team environment. Qualifications We Desire Broad knowledge of chemistry and materials. GPA of 3.0 or above.

Senior Explosives Research Experiment Lead | Lawrence Livermore National Laboratory

6 hours 32 minutes ago
Livermore, California, We have openings for Explosives Research Experiment Leads . You will lead experimental activities, under limited direction, involving the use of high explosives and other energetic materials, supporting the stewardship of the U.S. nuclear stockpile, conventional weapons design, counterterrorism efforts, and commercial partnerships. These positions are in the Strategic Deterrence (SD) Directorate. These positions may offer a hybrid schedule, blending in-person and virtual presence. You may have the flexibility to work from home one or more days per week. These positions will be filled at either the SES.3 or SES.4 level depending on your knowledge, skills and experience as assessed by the hiring team. Additional job responsibilities (outlined below) will be assigned if you are selected at the higher level. In this role you will Plan, execute, diagnose, analyze, and interpret explosively driven hydrodynamic experiments in collaboration with diagnostics operators, other scientists and high-level technical personnel, independently with minimal direction and at various state-of-the-art facilities across the DOE weapons complex. Manage and oversee multiple parallel, complex experiments at different stages of development and execution. Champion and/or lead original scientific/engineering projects to further the design of hydrodynamic experiments, applying knowledge and skills. Develop experimental requirements and oversee the implementation of the various components of the experiment. Identify, advocate and facilitate the addition of advanced diagnostics and data analysis techniques for explosively driven hydrodynamic experiments. Work with diagnostic designers to develop and integrate new capabilities. Perform technical quality assurance checks on these experiments including performing or directing others to perform the setup, alignment, and execution of the confirmatory dry runs to ensure that the expected data returned on the ultimate experiment will be of the highest quality possible within funding targets. Analyze and interpret complex experimental data, document and report results, identify problems, plan projects to solve problems, and communicate lessons learned. Present and disseminate research results to sponsors, and document experiment and results in open and classified environments. Recognize and support plans to promote and foster a culture of inclusion, diversity, equity, and accountability within the workplace. Travel based on needs of projects (minimally or substantially). Perform other duties as assigned. Additional job responsibilities at the SES.4 level Independently develop expertise in interrelated fields of physics, diagnostic techniques, or data analysis methods important to the design and execution of hydrodynamic experiments. Anticipate project shortcomings in advance and direct resources to develop effective solutions to improve efficiency in key areas relevant to hydrodynamic experiments. Champion and/or lead projects requiring involvement of broader scientific community external to LLNL. Ability to obtain and maintain a U.S. DOE Q-level security clearance, which requires U.S. citizenship. Master's degree in physics, engineering, a related field, or equivalent combination of education and related experience. Advanced knowledge of a specific area of science applicable to hydrodynamic testing Experience performing hands-on experimental science in bench top and/or test facility environments and familiarity with experimentation requiring formal conduct of operations. Experience managing medium-sized technical projects. Self-motivation and initiative in addressing challenging problems, and innovative ability to identify/develop creative solutions. Significant experience completing and/or leading top-quality research in relevant areas of physics and engineering. Ability to travel. Advanced interpersonal skills and emotional intelligence necessary to work effectively with a wide range of personalities in both one-on-one and team environments. Advanced written and verbal communication skills necessary to collaborate, present, and explain experimental design including proficiency in standard office computing software. Additional qualifications at the SES.4 level PhD in physics, engineering, a related field, or equivalent combination of education and related experience. Subject-matter expertise in one or more specific areas of science applicable to hydrodynamic testing. Significant experience leading large, multi-organizational technical projects. Ability to lead and mentor others in part of a multidisciplinary team. Substantial experience presenting and disseminating highly advanced research results at scientific conferences and peer-reviewed publications, in open and classified environments, internal and external to LLNL. Substantial experience communicating results of work with external sponsors. Qualifications We Desire Experience working around explosives and/or with other high-hazard materials or effects. Experience using computer-aided design tools. Experience with one or more of the following topics: dynamic radiography, high-speed photography, Photonic Doppler Velocimetry, radiometry, pulsed power (flash lamps, fire sets), system-generated EMP, grounding and shielding, modeling transmission and effects of ionizing radiation. Experience with scientific data analysis in mainstream programming languages or tools such as C++, Python, MATLAB, etc. Knowledge of the SD weapons program and/or explosive hydrodynamic experimentation. Demonstrated ability/commitment to promote and value inclusion, diversity, equity, and accountability principles in the workplace.

Explosives Research Experiment Lead | Lawrence Livermore National Laboratory

6 hours 32 minutes ago
Livermore, California, We have openings for an Explosives Research Experiment Lead . You will lead experimental activities, under general direction, involving the use of high explosives and other energetic materials, supporting the stewardship of the U.S. nuclear stockpile, conventional weapons design, counterterrorism efforts, and commercial partnerships. These positions are in the Strategic Deterrence Directorate. These positions may offer a hybrid schedule, blending in-person and virtual presence. You may have the flexibility to work from home one or more days per week. These positions will be filled at either the SES.2 or SES.3 level depending on your skills. Additional job responsibilities (outlined below) will be assigned if you are selected at the higher level. In this role, you will Plan, execute, diagnose, analyze and interpret explosively driven hydrodynamic experiments in collaboration with diagnostics operators, other scientists and high-level technical personnel, under limited direction and at various state-of-the-art facilities across the DOE weapons complex. Contribute original scientific/engineering solutions to the design of hydrodynamic experiments, applying knowledge and skills. Develop experimental requirements and assist or oversee the implementation of various components of the experiment. Perform, arm, fire, and diagnose experiments using highly explosive material. Monitor the assembly of the experimental hardware to ensure that the complex assemblies meet specification. Perform technical quality assurance checks on experiments including performing or directing others to perform the setup, alignment, and execution of the confirmatory dry-runs to ensure that the expected data returned on the ultimate experiment will be of the highest quality possible within funding targets. Analyze and interpret complex experimental data, document and report results, identify problems, plan projects to solve problems, and communicate lessons learned. Present and disseminate research results to sponsors, and document experiment and results in open and classified environments. Travel based on needs of projects, minimally or substantially. Recognize and support plans to promote and foster a culture of inclusion, diversity, equity, and accountability within the workplace. Perform other duties as assigned. In Addition, at the SES.3 Level Independently develop and/or provide in-depth technical expertise with multi-physics and other advanced computational tools to help model the expected performance of diagnostics where complex problems may not be well defined. Manage and oversee multiple parallel, complex experiments at different stages of development including the arming and firing of these experiments. Identify, advocate and facilitate the addition of advanced diagnostics and data analysis techniques for explosively driven hydrodynamic experiments. Work with diagnostic designers to develop and integrate new capabilities. Champion and/or lead projects requiring careful planning and execution in concert with effective teamwork. Ability to obtain and maintain a U.S. DOE Q-level security clearance which requires U.S. Citizenship. Master's Degree or PhD in physics, engineering, a related field, or equivalent combination of education and related experience. Comprehensive understanding of a specific area of science applicable to hydrodynamic testing. Experience performing hands-on experimental science in bench top and/or test facility environments and familiarity with experimentation requiring formal conduct of operations. Experience managing medium-sized or larger technical projects. Demonstrated self-motivation and initiative in addressing challenging problems, and innovative skills to identify/develop creative solutions. Experience working effectively in independent and in a multi-disciplinary, team-based-research environment to achieve multi-year goals. Interpersonal skills and emotional intelligence necessary to work effectively with a wide range of personalities in both one-on-one and team environments. Proficient written and verbal communication skills necessary to explain, negotiate and advise on experimental design including proficiency in standard office computing software. Additional qualifications at the SES.3 Level Advanced knowledge of physics, engineering, mathematics, mechanical, aerospace or nuclear engineering or a related field. Significant experience and demonstrated ability to lead and mentor a multidisciplinary team. Demonstrated record of completing and/or leading top-quality research in relevant areas of physics and engineering. Qualifications We Desire Experience working around explosives and/or other high hazard materials or effects. Experience using computer aided design tools Experience managing other personnel in a team environment Experience diagnosing very fast transient phenomena Experience modeling transmission and effects of ionizing radiation. Experience with any of the following topics: dynamic radiography, high speed photography, Photonic Doppler Velocimetry, radiometry, pulsed power (flash lamps, fire sets), system generated EMP, grounding and shielding. Experience with scientific data analysis in mainstream programming languages or tools such as C++, Python, MATLAB, etc. Knowledge of the Strategic Deterrence weapons program and/or explosive hydrodynamic experimentation Demonstrated ability/commitment to promote and value inclusion, diversity, equity, and accountability principles in the workplace.

Neuroscientist | Lawrence Livermore National Laboratory

6 hours 32 minutes ago
Livermore, California, NOTE: This is a flexible term position dependent on project funding. Current funding is expected for at least 2 years. The Bioscience and Biotechnology division within Physical and Life Sciences at LLNL is seeking to fill a position for a dedicated and hardworking Research Scientist with a background in Neuroscience with demonstrated experience in behavioral assessments, electrophysiology and other advanced molecular biology approaches. In this position, you will direct and conduct advanced cell and animal biology research, contributing to our understanding of the brain for mission relevant programs. Your role will involve working on defined research projects, where you will be expected to demonstrate initiative, resourcefulness, and a keen attention to detail within a multidisciplinary team of scientists. This position is in the Human Health Sciences Group in the Biosciences and Biotechnology Division. In this role you will: Lead and implement in vitro experiments that include both 2D and 3D rat and human cell models Collaborate with other scientists for in vivo experiments including behavioral assays/analyses Utilize advanced cell and molecular biology techniques to investigate and understand mechanisms of brain injury/repair Evaluate large data sets to refine, inform, and design subsequent experiments. Conduct literature reviews on state-of-the-art approaches relevant to the problem being addressed. Train and mentor early career and technician level staff Collaborate and interact with inter-organizational contacts and/or external customers. Prepare and present technical reports Ability to secure and maintain a U.S. DOE Q-level security clearance which requires U.S. Citizenship. Ph.D. in Neuroscience or related field, or the equivalent combination of education and related experience. Significant experience with human and rat neuronal cell cultures including electrophysiology, immunostaining and other assays including flow cytometry and multi-omics. Proficiency in R for data analyses. Advance knowledge of statistics for longitudinal datasets. Significant experience with animal handling, sample collection and behavioral testing Significant experience with multi-omics sample preparation and analyses. Significant experience in a fast-paced environment and able to work both independently and as a team with a diverse set of scientists, engineers, and other technical and administrative staff. Advanced knowledge of common software (e.g., Microsoft Office applications) and able to quickly learn new software.
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