Interview with Lonnie Thompson, Distinguished University Professor at Ohio State University and Senior Scholar at the Byrd Polar and Climate Research Center. Thompson describes the administrative history of the Byrd Center and he surveys his current field work in ice core drilling and the role of theory in his research. He provides his perspective on how humanity should respond to climate change and why natural climate fluctuations do not explain the current climate situation. Thompson recounts his childhood in West Virginia and the opportunities that allowed him to pursue a degree in physics at Marshall University. He discusses his graduate research at Ohio State in geophysics and geology while serving in the Army Reserves, and he describes how he developed the Byrd Center. Thompson describes his field work in China and Russia and the value of drilling across the planet. He discusses his work with Al Gore on An Inconvenient Truth and he conveys his feelings about winning the National Medal of Science. Thompson describes working with his wife Ellen Mosley-Thompson as his closest collaborator and what he has learned about conveying his scientific findings to the public. He reflects on the meaning of environmental heroism and the remaining field work that needs to be done after nearly 50 years of drilling. At the end of the interview, Thompson describes his current interest in finding and preserving biodiversity and why the next frontier for ice core drilling will be on Mars and beyond.