Chairman of the President's Science Advisory Committee. Science-government relationship; funding of basic research influenced by politics; development of basic research since World War II in physics, astronomy, medicine, geology, environment (Greenhouse Effect), agricultural; difference between funding procedures of Federal government and National Science Foundation. Extensive discussion of space exploration program. DuBridge's role and goals during his second term as PSAC chairman (first term was under President Eisenhower, 1952-1957); discussion of a science cabinet post (as opposed to a science advisor). Functions of PSAC; danger of development of a military-industrial complex. Role of Office of Naval Research in basic research after World War II. Comments on "vested interests;" military and technological enterprises in industry; growing dependence of universities on government money. Social implications of scientific and technological advances.