Interview with John Martinis, professor of physics at UC Santa Barbara. Martinis gave the interview from Australia, where he was consulting for Silicon Computing following his affiliation with Google’s efforts to build a quantum computer. He surveys the current state of play toward that goal, and explains what applications quantum computing can serve, and how the field is clarifying the technological requirements to achieve a quantum computer. Martinis recounts his childhood in Los Angeles, his early interests in computers, and his undergraduate experience at Berkeley where he gravitated toward experimental physics. He describes his interactions with John Clarke and his motivations to stay at Berkeley for graduate school, where he focused on SQUIDS and was captivated by Tony Leggett’s ideas on quantum tunneling. Martinis explains his interest in working with Michel Devoret at Saclay for his postdoctoral research, where there was much excitement over high Tc and YBCO materials. He describes his subsequent work at NIST and his decision to join the faculty at Santa Barbara around the time he became focused on quantum computing. Martinis narrates the technological challenges of building qubits and error correction, and he explains how he got involved with Google and joined his style with its research culture. He describes his role as chief scientist in the collaboration and why his vision and Google’s diverged. Martinis addresses the issue of “hype” in quantum computing. At the end of the interview, Martinis emphasizes the centrality of systems engineering to his research agenda, and he explains why quantum supremacy will demonstrate the need for quantum computing and the limitations of classical computing.