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Student years at University of Cambridge, 1919-1923; move to Harvard University in 1923, and subsequent career. Comments on being a woman studying physics at Cambridge in the 1920s; influences of Ernest Rutherford, Arthur Eddington and Edward Milne on her career choice; some of her early research. Move to Harvard (inspired by lecture by Harlow Shapley). At Harvard, work (virtually alone) on stellar spectra; encouragement of Shapley and Annie J. Cannon. Publications on stellar atmospheres and variable stars; anecdotes about including E.C. Pickering, Henry N. Russell, Raymond S.