Interview with Peter Lepage, Tisch Family Distinguished University Professor of Physics at Cornell. He recounts his childhood in Montreal and his decision to pursue an undergraduate degree in physics at McGill. Lepage discusses his Master’s work at Cambridge University and his decision to do his thesis research in particle physics at Stanford. He describes the fundamental advances happening at SLAC during his graduate years and his work on bound states of electrons and muons under the direction of Stanley Brodsky. Lepage discusses his postdoctoral appointment at Cornell and his work in high-precision QED calculations in atoms, and he describes the foundational impact of Ken Wilson’s work on lattice QCD and the intellectual revolution of renormalization. He describes this period as his entrée into QCD research, and he emphasizes the beauty of Ithaca and the supportive culture of the Physics Department as his main reasons to accept a faculty position at Cornell. Lepage explains how and when computers became central to Lattice QCD research and why effective field theory was an area of specialization that was broadly useful in other subfields. He describes the ongoing stubbornness of the Standard Model, and he discusses his tenure as chair of the department, then as Dean of the College of Arts and Sciences, and his work on PCAST in the Obama administration. Lepage explains his longstanding interest in physics pedagogy, and he discusses his current work on the numerical integration program called VEGAS. In the last part of the interview, Lepage emphasizes that the most fundamental advances in physics are in astrophysics and cosmology and that lattice QCD should be “kept alive” because it’s unclear where it is going until physics goes beyond the Standard Model.