In this interview, David Zierler, Oral Historian for AIP, interviews Joseph Silk, Homewood Research Professor of Physics at Johns Hopkins, Researcher Emeritus at the Institute of Astrophysics in Paris, and Senior Fellow at the Beecroft Institute for Cosmology and Astro-Particle Physics. Silk recounts his childhood in London as the child of working-class parents, and he describes his early interests in math and his acceptance to Cambridge. He discusses the influence of the fluid dynamicist George Batchelor and the gravitational theorist Denis Sciama, and his decision to pursue graduate work at Manchester before enrolling at Harvard for his PhD research under the direction of David Layzer. Silk describes the revolutionary discovery of the cosmic microwave background and some of the observational advances that were driving the young field of cosmology and galaxy formation. He discusses his postdoctoral appointment with Fred Hoyle back at Cambridge and his next research position working with Lyman Spitzer at Princeton, and with Jerry Ostriker on black holes and pulsars. Silk describes the circumstances leading to his first faculty appointment at Berkeley and the excitement surrounding the high red shift universe, the birth of X-ray astronomy, and he describes Berkeley Laboratory’s gradual emphasis on astrophysics over his 30-year career at UC Berkeley. He discusses his long-term research endeavor to verify the prediction of the Big Bang theory and the incredible results of the COBE project. Silk describes his budding interests in particle astrophysics, which he considers a discipline distinct from astronomy, cosmology and astrophysics, and which grew from cosmic inflation. He describes the import and future prospects of supersymmetry, how his namesake contribution “Silk damping” came about, and he conveys his excitement about moon-based telescopes. Silk draws a distinction between understanding the very beginning of the universe (t = 0) and the tiniest fraction of time after that (t = epsilon) and why an understanding quantum gravity will be necessary to make advances in this field. He discusses the current controversy around the Hubble constant, he describes his decision to transfer from Berkeley to Oxford and how this led to his current slate of affiliations, including his appointment at Johns Hopkins. At the end of the interview, Silk discusses his current interests in the moon telescope project and what the legal ramifications of a permanent moon presence might look like and why, in his popular talks, he finds it important to project a sense of awe about the universe.