In this interview, Ilko Ilev, discusses his career as a Senior Biomedical Research Service Scientist within the U.S. Health and Human Services Department. He details getting his PhD from the Technical University of Sofia in laser physics, where his thesis was focused on the development of alternative effective laser designs with direct lens-free optical fiber outputs and their implementations towards nonlinear broadband frequency conversions in optical fibers. Ilev details his experience as a Senior Assistant Professor at the Technical University of Sofia where he taught courses on general physics, quantum electronics, and fiber optics. He discusses the relationship between the FDA and medical device manufacturers. He describes the FDA’s longstanding collaboration with the Uniformed Service University of the Health Sciences, which has resulted in the development of a new field, Photobiomodulation Therapeutics. Lastly, Ilev discusses the various ways in which physics is directly applicable to his work.