Interview with William Duax, professor emeritus at the Hauptman-Woodward Institute. Duax recounts his childhood in Illinois, and he describes his early interests in the theater and bee keeping, before he focused on science at St. Ambrose University. He describes his decision to pursue a Ph.D. in chemistry at the University of Iowa, and he talks about his introduction to quantum chemistry and X-ray crystallography. Duax discusses his postdoctoral research growing crystals with Abe Clearfield at Ohio University, and he explains the circumstances leading to his decision to join the faculty at HWI. He describes his developing interests in endocrinology and the formative influence of David Harker at the Roswell Park Research Crystallographic Center. Duax describes the long-term support of the NIH for his research agenda, and he discusses the value of his appointment at SUNY Buffalo. He recounts his long-term involvement in the American Crystallographic Association and his ongoing research interests in steroid structure and ribosomal proteins. Duax explains the importance of taking an evolutionary approach to his research, and he discusses some recent advances in bioinformatics. At the end of the interview, Duax describes his interest in social justice movements, and in particular, Black Lives Matter, and he explains the future promises of electron microscopy.