AIP and AIP Publishing congratulate Eric Betzig of the Howard Hughes Medical Institute, Stefan W. Hell of the Max Planck Institute for Biophysical Chemistry and the German Cancer Research Center, and William E. Moerner of Stanford University for winning the 2014 Nobel Prize in Chemistry "for the development of super-resolved fluorescence microscopy."
On this page, you will find:
» Seminal papers by the Laureates (free access through 12/31/14)
» Further work by the Laureates related to SRFM and STED techniques (free access through 12/31/14)
» Additional articles related to SRFM and STED techniques in AIP Publishing journals (free access through 12/31/14)
» From OSA Publishing—more than 150 related articles and conference proceedings (free access for 60 days)
2014 Chemistry Nobel Prize Resources →
Seminal Papers by the Laureates (free access through 12/31/14)
Super‐resolution fluorescence near‐field scanning optical microscopy
A. Harootunian, E. Betzig, M. Isaacson and A. Lewis
Appl. Phys. Lett. 49 , 674 (1986)
Collection mode near‐field scanning optical microscopy
E. Betzig, M. Isaacson and A. Lewis
Appl. Phys. Lett. 51 , 2088 (1987)
Fluorescence lifetime three-dimensional microscopy with picosecond precision using a multifocal multiphoton microscope
M. Straub and S. W. Hell
Appl. Phys. Lett. 73 , 1769 (1998)
Two‐photon excitation 4Pi confocal microscope: Enhanced axial resolution microscope for biological research
P. E. Hänninen, S. W. Hell, J. Salo, E. Soini and C. Cremer
Appl. Phys. Lett. 66, 1698 (1995)
Subresolution axial distance measurements in far-field fluorescence microscopy with precision of 1 nanometer
Michael Schmidt, Matthias Nagorni, Stefan W. Hell
Rev. Sci. Instrum. 71, 2742 (2000)
Stimulated emission depletion microscopy with an offset depleting beam
T. A. Klar, M. Dyba and S. W. Hell
Appl. Phys. Lett. 78 , 393 (2001)
Methods of single-molecule fluorescence spectroscopy and microscopy
W. E. Moerner and David P. Fromm
Rev. Sci. Instrum. 74 , 3597 (2003)
The double-helix microscope super-resolves extended biological structures by localizing single blinking molecules in three dimensions with nanoscale precision
Hsiao-lu D. Lee, Steffen J. Sahl, Matthew D. Lew and W. E. Moerner
Appl. Phys. Lett. 100 , 153701 (2012)
Further work by the Laureates related to SRFM and STED techniques (free access through 12/31/14)
Measurement of the 4Pi‐confocal point spread function proves 75 nm axial resolution
S. W. Hell, S. Lindek, C. Cremer and E. H. K. Stelzer
Appl. Phys. Lett. 64 , 1335 (1994)
Potential of confocal microscopes to resolve in the 50–100 nm range
M. Schrader, S. W. Hell and H. T. M. van der Voort
Appl. Phys. Lett. 69 , 3644 (1996)
Three-dimensional super-resolution with a 4Pi-confocal microscope using image restoration
M. Schrader, S. W. Hell and H. T. M. van der Voort
J. Appl. Phys. 84 , 4033 (1998)
Ultrafast dynamics microscopy
M. Dyba, T. A. Klar, S. Jakobs and S. W. Hell
Appl. Phys. Lett. 77 , 597 (2000)
Depolarization by high aperture focusing
K. Bahlmann and S. W. Hell
Appl. Phys. Lett. 77 , 612 (2000)
Image amplification and novelty filtering with a photorefractive polymer
Arosha Goonesekera, Daniel Wright and W. E. Moerner
Appl. Phys. Lett. 76 , 3358 (2000)
Single sharp spot in fluorescence microscopy of two opposing lenses
C. M. Blanca, J. Bewersdorf and S. W. Hell
Appl. Phys. Lett. 79 , 2321 (2001)
Single-molecule optical spectroscopy of autofluorescent proteins
W. E. Moerner
J. Chem. Phys. 117 , 10925 (2002)
High-performance photorefractive organic glass with near-infrared sensitivity
Oksana Ostroverkhova, W. E. Moerner, Meng He and Robert J. Twieg
Appl. Phys. Lett. 82 , 3602 (2003) ; http://dx.doi.org/10.1063/1.1577214
Laser-diode-stimulated emission depletion microscopy
V. Westphal, C. M. Blanca, M. Dyba, L. Kastrup and S. W. Hell
Appl. Phys. Lett. 82 , 3125 (2003) ; http://dx.doi.org/10.1063/1.1571656
Spectral analysis of strongly enhanced visible light transmission through single C-shaped nanoapertures
J. A. Matteo, D. P. Fromm, Y. Yuen, P. J. Schuck, W. E. Moerner and L. Hesselink
Appl. Phys. Lett. 85 , 648 (2004) ; http://dx.doi.org/10.1063/1.1774270
Method for trapping and manipulating nanoscale objects in solution
Adam E. Cohen and W. E. Moerner
Appl. Phys. Lett. 86 , 093109 (2005) ; http://dx.doi.org/10.1063/1.1872220
Lithographic positioning of fluorescent molecules on high-Q photonic crystal cavities
Kelley Rivoire, Anika Kinkhabwala, Fariba Hatami, W. Ted Masselink, Yuri Avlasevich, Klaus Müllen, W. E. Moerner and Jelena Vučković
Appl. Phys. Lett. 95 , 123113 (2009) ; http://dx.doi.org/10.1063/1.3232233
Three-dimensional localization precision of the double-helix point spread function versus astigmatism and biplane
Majid Badieirostami, Matthew D. Lew, Michael A. Thompson and W. E. Moerner
Appl. Phys. Lett. 97 , 161103 (2010) ; http://dx.doi.org/10.1063/1.3499652
Improved transducer correction for standing‐wave ultrasonic velocity measurements
H. I. Ringermacher, W. E. Moerner and J. G. Miller
J. Appl. Phys. 45 , 549 (1974) ; http://dx.doi.org/10.1063/1.1663281
Phase sensitive detection of persistent spectral holes using synchronous ultrasonic modulation
W. E. Moerner and A. L. Huston
Appl. Phys. Lett. 48 , 1181 (1986) ; http://dx.doi.org/10.1063/1.96462
Fast burning of persistent spectral holes in small laser spots using photon‐gated materials
W. E. Moerner, T. P. Carter and C. Bräuchle
Appl. Phys. Lett. 50 , 430 (1987) ; http://dx.doi.org/10.1063/1.98164
Statistical fine structure in the inhomogeneously broadened electronic origin of pentacene in p‐terphenyl
T. P. Carter, M. Manavi and W. E. Moerner
J. Chem. Phys. 89 , 1768 (1988) ; http://dx.doi.org/10.1063/1.455123
Intracavity frequency doubling of a Nd:YAG laser with an organic nonlinear optical crystal
Stephen Ducharme, W. P. Risk, W. E. Moerner, Victor Y. Lee, R. J. Twieg and G. C. Bjorklund
Appl. Phys. Lett. 57 , 537 (1990) ; http://dx.doi.org/10.1063/1.103640
C60 sensitization of a photorefractive polymer
S. M. Silence, C. A. Walsh, J. C. Scott and W. E. Moerner
Appl. Phys. Lett. 61 , 2967 (1992) ; http://dx.doi.org/10.1063/1.108033
Electric field‐dependent nonphotorefractive gratings in a nonlinear photoconducting polymer
S. M. Silence, M. C. J. M. Donckers, C. A. Walsh, D. M. Burland, W. E. Moerner and R. J. Twieg
Appl. Phys. Lett. 64 , 712 (1994) ; http://dx.doi.org/10.1063/1.111043
Excitation of a single molecule on the surface of a spherical microcavity
D. J. Norris, M. Kuwata-Gonokami and W. E. Moerner
Appl. Phys. Lett. 71 , 297 (1997) ; http://dx.doi.org/10.1063/1.119554
High performance photorefractive polymer with improved stability
A. Grunnet-Jepsen, C. L. Thompson, R. J. Twieg and W. E. Moerner
Appl. Phys. Lett. 70 , 1515 (1997) ; http://dx.doi.org/10.1063/1.118604
High-speed photorefractive polymer composites
D. Wright, M. A. Dı́az-Garcı́a, J. D. Casperson, M. DeClue, W. E. Moerner and R. J. Twieg
Appl. Phys. Lett. 73 , 1490 (1998) ; http://dx.doi.org/10.1063/1.122182
High-performance photorefractive polymer composite with 2-dicyanomethylen-3-cyano-2,5-dihydrofuran chromophore
Daniel Wright, Ulrich Gubler, Yeonsuk Roh, W. E. Moerner, Meng He and Robert J. Twieg
Appl. Phys. Lett. 79 , 4274 (2001) ; http://dx.doi.org/10.1063/1.1428120
Additional articles related to SRFM and STED techniques in AIP Publishing journals (free access through 12/31/14)
Laser scanning confocal microscope with programmable amplitude, phase, and polarization of the illumination beam
B. R. Boruah and M. A. A. Neil
Rev. Sci. Instrum. 80, 013705 (2009); http://dx.doi.org/10.1063/1.3072663
Far-field optical nanoscopy based on continuous wave laser stimulated emission depletion
Cuifang Kuang, Wei Zhao and Guiren Wang
Rev. Sci. Instrum. 81, 053709 (2010); http://dx.doi.org/10.1063/1.3432001
Performance improvement in nanoparticle-assisted stimulated-emission-depletion nanoscopy
Yonatan Sivan
Appl. Phys. Lett. 101, 021111 (2012); http://dx.doi.org/10.1063/1.4735319
Tuning donut profile for spatial resolution in stimulated emission depletion microscopy
Bhanu Neupane, Fang Chen, Wei Sun, Daniel T. Chiu and Gufeng Wang
Rev. Sci. Instrum. 84, 043701 (2013); http://dx.doi.org/10.1063/1.4799665
Taylor series expansion based multidimensional image reconstruction for confocal and 4pi microscopy
Shilpa Dilipkumar and Partha Pratim Mondal
Appl. Phys. Lett. 103, 073702 (2013); http://dx.doi.org/10.1063/1.4817928
Spatial filtering nearly eliminates the side-lobes in single- and multi-photon 4pi-type-C super-resolution fluorescence microscopy
Kavya M., Raju Regmi and Partha P. Mondal
Rev. Sci. Instrum. 84, 093704 (2013); http://dx.doi.org/10.1063/1.4820922
Perspective: Reaches of chemical physics in biology
Martin Gruebele and D. Thirumalai
J. Chem. Phys. 139, 121701 (2013); http://dx.doi.org/10.1063/1.4820139
Annular solid-immersion lenslet array super-resolution optical microscopy
Z. L. Liau
J. Appl. Phys. 112, 083110 (2012); http://dx.doi.org/10.1063/1.4761813
A bisected pupil for studying single-molecule orientational dynamics and its application to three-dimensional super-resolution microscopy
Adam S. Backer, Mikael P. Backlund, Alexander R. von Diezmann, Steffen J. Sahl and W. E. Moerner
Appl. Phys. Lett. 104, 193701 (2014); http://dx.doi.org/10.1063/1.4876440