In this interview Wolfgang Panofsky discusses topics such as: his time at the High Energy Physics Laboratory at Stanford University; Stanford Linear Accelerators Center (SLAC); Atomic Energy Commission (AEC); Edwin McMillan; Burton Richter; running a physical laboratory; Luis Alvarez; the Cold War; University of California, Berkeley; teaching and setting up research projects for graduate students; serving on the President's Science Advisory Committee; Robert Marshak; McCarthyism and House Committee on Un-American Activities; Paul McDaniel; Vietnam War's effect; working with Chinese physicists; Frank Oppenheimer; Department of Energy; safety measures in the laboratories; arms control; Marvin Goldberger; JASON group; Richard Garwin; John Holdren.