Interview with Sean O’Keefe, Professor at the Syracuse University Maxwell School of Citizenship and Public Affairs. O’Keefe describes moving around as a child when his father worked for the Navy. He discusses his undergraduate work at Loyola in New Orleans, and he explains his interest in pursuing a career in public service in the post-Watergate, post-Vietnam era when there was much cynicism about working for the government. O’Keefe describes his participation in the Presidential Management Intern Program and his work for the Department of the Navy and after that, for the Appropriations Committee on Capitol Hill, where he worked on budgetary policy against the backdrop of the Cold War in the 1980s. He describes his work at Comptroller for the Department of Defense where he worked on identifying budgetary waste at the Pentagon. O’Keefe describes the scene at the Pentagon during the Gulf War, and he discusses the opportunity that led to him becoming Secretary of the Navy. He describes his career prospects outside of government after George H.W. Bush lost re-election and the opportunity leading to his professorship at Syracuse University, where he mentored students in public service leadership. O’Keefe describes being named NASA administrator in the administration of George W. Bush and some of the challenges he encountered coming from a defense background. He discusses the tragedy and his strategy in dealing with the Space Shuttle Columbia disaster, both in terms of lessons learned from the engineering failures, and the grief that he shared with the families of the astronauts who died. O’Keefe describes some of the ways he attempted to turn the disaster into institutional opportunity at NASA and its impact on the Hubble space servicing mission. He describes his decision to become Chancellor at Louisiana State University, where he focused on building up the school’s endowment, dealing with Hurricane Katrina, and working to keep LSU graduates in the state. O’Keefe describes his tenure as CEO of Airbus North America before returning to Syracuse to teach in his current position. At the end of the interview, O’Keefe reflects on what he has learned about organizational leadership over the course of his career, and what he tries to convey to his students as they prepare to become the nation’s next generation of leaders.