This interview is part of a series conducted during research for the book Tunnel Visions, a history of the Superconducting Super Collider. It also covers a range of other topics concerning George (Jay) Keyworth’s service between 1981 and 1985 as science advisor to President Ronald Reagan. Keyworth recounts his previous career at Los Alamos Scientific Laboratory, his selection as science advisor, his access to White House policymaking via counselor to the president Ed Meese, and his own interactions with Reagan. He notes that Reagan had a faith in technological ingenuity as part of a broadly optimistic outlook on humanity. Keyworth also discusses his strong relationship with engineer and executive David Packard as well as deliberations concerning stealth technology, missile basing, the AIDS crisis, and space policy. He expresses disdain for the space station and space shuttle programs and his regret that the Reagan administration did not do more to reform NASA. He recalls spending political capital securing White House support for basic research, including the SSC and funding increases for the National Science Foundation. He argues that Brookhaven National Lab’s Isabelle collider was poorly justified whereas the SSC was an ambitious and inspiring project. Keyworth asserts that he was able to commit the White House Office of Management and Budget to pursuing the SSC before he was assigned full-time to working on the Strategic Defense Initiative ballistic missile defense program in 1983.