In this interview, Edward Creutz discusses topics such as: his family background; Gregory Breit; doing his postgraduate work at the University of Wisconsin on nuclear physics; Ray Herb; Julian Mack; Fred de Hoffmann; Eugene Wigner; going to Princeton as a research assistant working on the small cyclotron; Carnegie Institute of Technology; Frederick Seitz; Office of Naval Research (ONR); Urner Liddel; Atomic Energy Commission (AEC); helping to build the first commercial nuclear reactor; working in the metallurgical lab at the University of Chicago working on the metallurgy of uranium; Genera