In this interview, Andrea Dupree discusses topics such as: her family background and childhood; doing her undergraduate studies at Wellesley College; Janet Guernsey; C. P. Snow; becoming interested in astronomy; what is was like being a woman and fitting into the physics profession and dealing with gender inequality; Sarah Hill; Allan Sandage; Hans Bethe; Phil Morrison; Otto Struve; going to the Royal Greenwich Observatory for a summer; Cecilia Payne-Gaposchkin; Dorrit Hoffleit; variable star fields; deciding to go to Berkeley for graduate school; Ivan King; Hyron Spinrad; Lick Observatory; coming back to Harvard University after a year; George Wallerstein; William Liller; Leo Goldberg; her affiliation with the American Astronomical Society (AAS); Don Osterbrock; Simon "Pete" Worden; Owen Chamberlain; Alex Dalgarno; Harvard College Observatory; Harvard-Smithsonian Center for Astrophysics; Ed Lilley; solar physics; ionization rates; Herb Friedman; Dick Tousey; Henry Smith; stellar atmospheres; Fred Whipple; Donald Menzel; Margaret Burbidge; orbiting solar observatories (OSO); Skylab program; Lyman Spitzer; Robert Noyes; Henry Norris Russell; International Astronomical Union (IAU); National Aeronautics and Space Administration (NASA); George Field; Smithsonian Astrophysical Observatory (SAO); Eric Chaisson; Jesse Greenstein; Celescope.