Donald Witters recently retired as a Senior Review Scientist from the FDA, Center for Devices and Radiological Health. In this interview, Witters recounts his childhood in suburban Washington DC, and his decision to pursue a physical sciences degree at the University of Maryland. He describes meeting Howard Bassen and the opportunity to join the FDA and he explains the overall mission of the FDA’s work on technology regulation for public health, including the regulation of microwave ovens, X-rays, and electric and radio fields. Witters explains how regulatory questions reached his office, and how he and his colleagues transmitted information as part of the process of regulatory policy. He discusses the role of the FDA in regulatory medical devices and the research that demonstrated that cell phones did not produce a hazardous level of radiation. Witters describes the many challenges associated with RFID and avoiding interference with medical devices such as pacemakers. At the end of interview, Witters surveys the regulatory work that will be needed for the wireless 5G network, and he describes the value in completing a graduate program at Georgetown in biomedical engineering.