Interview with Michal Lipson, Eugene Professor in the Departments of Electrical Engineering and Applied Physics at Columbia University. She recounts her childhood as the daughter of a prominent physicist whose work took the family to Israel and then in Brazil, where she spent her formative years in São Paulo. Lipson explains her decision to pursue a degree in physics at Technion in Israel, where she remained to complete her graduate studies in semiconductor physics under the direction of Elisha Cohen. She describes her postdoctoral research at MIT in material science with Lionel Kimerling, and she explains the opportunities that led to her first faculty position at Cornell. Lipson describes her dual interest in pursuing basic science research and industry-relevant work. She discusses her work in photonics which led to her MacArthur fellowship and the significance of her study of slot waveguides and optical amplification in silicon. Lipson describes her subsequent work in nonlinear photonics and high-power lasers, and she explains the opportunity leading to her current position at Columbia, where she has focused on two-dimensional materials. At the end of the interview, Lipson emphasizes the fundamental importance of oscillators that have always informed her research.