Inside Science
/
Article

Spider Venom Could Ease Your Pain

OCT 29, 2013
Chemists are studying tarantula venom to develop new drugs.
Spider Venom Could Ease Your Pain

Poisonous spiders may seem scary, but their venom could lead to better pain medications.

Chemist Greg Holland of Arizona State University thinks that poisonous spiders have been given a bad rap. He’s collecting venom from tarantulas to learn more about their toxic poison and how it can potentially help people.

“Some of the proteins that have been discovered in venom can be used as drugs,” Holland said.

Using nuclear magnetic resonance – much like an MRI – scientists can learn about tiny structures in spider venom.

“Their complete three-dimensional structure has not been solved, so we are working towards solving the structure, which will allow us to better understand how they work and function in the body,” he said.

Researchers want to learn more about certain protein structures in venom, which they hope could turn human pain receptors on and off, like painkiller medications.

“Structure directly relates to how something functions, so in order to understand its function, you have to solve its structure.” said Holland.

Researchers want to learn more about certain protein structures in venom, which they hope could turn human pain receptors on and off – like painkiller medications. They’ve also learned that venom could help control some heart rhythm problems like arrhythmias.

Why use venom from these spiders?

“Tarantulas are fairly large,” Holland said. “They produce a fair amount of venom compared to smaller spiders so it gives us a larger source.”


Get Inside The Science:

Greg Holland, Arizona State University

More Science News
/
Article
Previously unreported slow conformational changes in COVID-19 virus protease–drug complexes reveal hidden bound states relevant to antiviral drug design.
/
Article
3D printed scaffolds and sensors promise to improve surgical fracture care and management.
/
Article
Multiphase flow dynamics in immersion lithography govern the yield and defect density of semiconductor manufacturing.
/
Article
Imaging system exploits adaptive optics to capture high-resolution video of fast-moving electrical activity in the brain.
/
Article
/
Article
Students from numerous countries gathered in Sweden and Colombia to solve challenging theoretical and experimental physics problems.
/
Article
Academics in the child-friendly nation face career disadvantages, such as lower employment rates, after becoming parents.