News & Analysis
/
Article

Silicon quantum dots have a bright future in bio-imaging

APR 11, 2025
Providing a non-toxic alternative to chalcogenides, silicon quantum dot hybrid systems have a promising future in optogenetics, phototherapy and more.
Silicon quantum dots have a bright future in bio-imaging internal name

Silicon quantum dots have a bright future in bio-imaging lead image

Semiconductors with quantum dots are a rising star in the world of photonic technologies. However, traditional quantum dots are made with metal chalcogenide nanoparticles, which are toxic. Silicon offers a promising alternative given its abundance, non-toxicity and broad photoluminescence spectral range. Wang and Tang provide a comprehensive look at the state and future of silicon quantum dot hybrid systems.

The review looks at silicon quantum dot’s optical properties, photophysical parameters, and energetics. Recent examples and applications of silicon quantum dots are also discussed along with current issues and future prospects.

Silicon quantum dot hybrids have already been used in a range of applications, such as solar cells, LEDs and solar concentrators. Notably, these hybrids also show great promise for photon upconversion, a process which combines two photons into one high energy photon. Photon upconversion is useful for technologies like high-resolution bioimaging and modern photovoltaic technologies.

“The most important future application for Si QDs will be in biology for optogenetics or phototherapy, or to detect oxygen levels in biocompatible scaffolds to make artificial tissue,” said author Ming Lee Tang.

However, some limitations to silicon quantum dots remain, including their low absorption coefficient at visible wavelengths and their high defect density at the surface, including dangling bonds. Several ideas have been proposed to resolve these issues, but more research is needed. For example, to help low absorption coefficients, organic molecules as visible light absorbers could be used.

“The investigation of Si-molecule hybrid systems is still in its infancy,” Tang said. “Detailed and systematic explorations on Si QD-molecule hybrid systems are necessary and significant for their promising applications in the future.”

Source: “Silicon quantum dot-molecule hybrid systems and their applications,” by Kefu Wang and Ming Lee Tang, Journal of Chemical Physics (2025). The article can be accessed at https://doi.org/10.1063/5.0249392 .

More Science
/
Article
Diffuse correlation spectroscopy and a machine learning algorithm can provide continuous blood pressure feedback, enabling real-time monitoring during surgery and for at-risk patients.
/
Article
Computational approach offers insights into hemodynamics and pulsatile blood flow.
/
Article
A hybrid approach simulates the breakup and entrapment of water droplets in hypersonic vehicles’ air flow fields.
AAS
/
Article
Astronomers have found a baby system that’s just beginning to build planets — and it can tell us about how and where planet formation starts.